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4-Methylhistamine

From Wikipedia, the free encyclopedia
4-Methylhistamine
Names
Preferred IUPAC name
2-(5-Methyl-1H-imidazol-4-yl)ethan-1-amine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard100.163.601Edit this at Wikidata
KEGG
MeSH4-methylhistamine
UNII
  • InChI=1S/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9) checkY
    Key: UGYXPZQILZRKJJ-UHFFFAOYSA-N checkY
  • InChI=1/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9)
    Key: UGYXPZQILZRKJJ-UHFFFAOYAJ
  • CC1=C(N=CN1)CCN
Properties
C6H11N3
Molar mass125.17164 g/mol
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

4-Methylhistamine is ahistamine agonist selective for theH4 subtype.[1]

References

[edit]
  1. ^Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL, Leurs R (September 2005)."Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist".J. Pharmacol. Exp. Ther.314 (3):1310–21.doi:10.1124/jpet.105.087965.PMID 15947036.S2CID 24248896.
H1
Agonists
Antagonists
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
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