 | |
| Names | |
|---|---|
| Preferred IUPAC name 3-Sulfanylpropanoic acid | |
| Other names 3-MPA; 3-Mercaptopropanoic acid; β-Mercaptopropionic acid | |
| Identifiers | |
3D model (JSmol) | |
| 773807 | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.003.216 |
| EC Number |
|
| 101294 | |
| UNII | |
| |
| |
| Properties | |
| C3H6O2S | |
| Molar mass | 106.14 g·mol−1 |
| Density | 1.218 |
| Melting point | 16.9 °C (62.4 °F; 290.0 K) |
| Boiling point | 111 °C (232 °F; 384 K) at 15 mmHg[1] |
| soluble | |
| Solubility | ether benzene alcohol water |
| Acidity (pKa) | 4.34 |
Refractive index (nD) | 1.4911 at 21 °C |
| Hazards | |
| GHS labelling: | |
   | |
| Danger | |
| H290,H301,H314,H332 | |
| P234,P260,P261,P264,P270,P271,P280,P301+P310,P301+P330+P331,P303+P361+P353,P304+P312,P304+P340,P305+P351+P338,P310,P312,P321,P330,P363,P390,P404,P405,P501 | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
3-Mercaptopropionic acid (3-MPA) is anorganosulfur compound with the formula HSCH2CH2CO2H. It is abifunctional molecule, containing both carboxylic acid and thiol groups. It is a colorless oil. It is derived from the addition of hydrogen sulfide toacrylic acid.
It is competitive inhibitor ofglutamate decarboxylase, and therefore acts as aconvulsant. It has higherpotency and fasteronset of action compared toallylglycine.[2]
It is used to prepare hydrophilicgold nanoparticles, exploiting the affinity of gold for sulfur ligands.[3]
It is esterified withpolyols to form thiol-basedpolymer cross-linking agents such aspentaerythritol-basedpentaerythritol tetrakis(3-mercaptopropionate).[4]
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