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3,4-Methylenedioxy-N-methylphentermine

From Wikipedia, the free encyclopedia

Pharmaceutical compound
MDMP
Clinical data
Other namesMDMP; MDMPH; 3,4-Methylenedioxy-α,α,N-trimethylphenethylamine
Routes of
administration
Oral[1]
ATC code
  • None
Pharmacokinetic data
Duration of action"Perhaps 6 hours"[1]
Identifiers
  • 1-(2H-1,3-benzodioxol-5-yl)-N,2-dimethylpropan-2-amine
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC12H17NO2
Molar mass207.273 g·mol−1
3D model (JSmol)
  • CC(C)(NC)Cc1ccc2OCOc2c1
  • InChI=1S/C12H17NO2/c1-12(2,13-3)7-9-4-5-10-11(6-9)15-8-14-10/h4-6,13H,7-8H2,1-3H3
  • Key:CRFWCCGPRXKZSM-UHFFFAOYSA-N

3,4-Methylenedioxy-N-methylphentermine (MDMP orMDMPH), also known as3,4-methylenedioxy-α,α,N-trimethylphenethylamine, is a lesser-knowndrug.[1]

Use and effects

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MDMP was first synthesized byAlexander Shulgin.[1] In his bookPiHKAL, the minimum dose is listed as 110 mg, and the duration is listed as approximately 6 hours.[1] MDMP produces few to no effects, and is slightly similar toMDMA.[1]

Pharmacology

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Pharmacodynamics

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MDMP failed to act as aserotonin releasing agent in rat brainsynaptosomesin vitro.[2][3][4]

Society and culture

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Legal status

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United Kingdom

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This substance is a Class A drug in theDrugs controlled by the UK Misuse of Drugs Act.[5]

See also

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References

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  1. ^abcdefShulgin A,Shulgin A (September 1991).PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press.ISBN 0-9630096-0-5.OCLC 25627628.MDMP entry
  2. ^Nichols DE, Oberlender R (1989)."Structure-activity relationships of MDMA-like substances"(PDF).NIDA Research Monograph.94:1–29.PMID 2575223. Archived fromthe original(PDF) on May 11, 2023.
  3. ^Nichols DF, Oberlender R (1990)."Structure-Activity Relationships of MDMA and Related Compounds: A New Class of Psychoactive Agents?".Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA. Topics in the Neurosciences. Vol. 9. Boston, MA: Springer US. pp. 105–131.doi:10.1007/978-1-4613-1485-1_7.ISBN 978-1-4612-8799-5.PMID 1979214. Retrieved19 November 2025.
  4. ^Nichols DE, Lloyd DH, Hoffman AJ, Nichols MB, Yim GK (May 1982). "Effects of certain hallucinogenic amphetamine analogues on the release of [3H]serotonin from rat brain synaptosomes".Journal of Medicinal Chemistry.25 (5):530–535.doi:10.1021/jm00347a010.PMID 7086839.
  5. ^"UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Archived fromthe original on 22 October 2017. Retrieved12 March 2014.
Phenethylamines
Amphetamines
Phentermines
Cathinones
Phenylisobutylamines
(and further-extended)
Catecholamines
(and close relatives)
Cyclized
phenethylamines
Phenylalkylpyrrolidines
2-Benzylpiperidines
(phenidates)
Phenylmorpholines
(phenmetrazines)
Phenyloxazolamines
(aminorexes)
Isoquinolines and
tetrahydroisoquinolines
2-Aminoindanes
2-Aminotetralins
Others / unsorted
Related compounds
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