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| Formula | C14H18FNO |
| Molar mass | 235.302 g·mol−1 |
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2F-NENDCK (CanKet, 2-Fluoro-N-Ethylnordeschloroketamine,2'-Fluoro-2-Oxo-Phenylcyclohexylethylamine,2'-Fluoro-2-Oxo-PCE) is a recreationaldesigner drug from thearylcyclohexylamine family, withdissociative effects presumably similar to those ofketamine. Its general effects, dissociative or otherwise, may deviate from otherarylcyclohexylamines.
It was initially identified inCanberra, Australia in mid-August 2022 by the government-funded drug-testing service CanTEST.[1] It has since been dubbed "CanKet" due to it originally being found inCanberra and being astructural analogue ofketamine.[2][3] It has subsequently been discovered inTaiwan,China andNew Zealand.[4][5][6]
Due to the lack of research pertaining to it, there are no known legitimate uses for CanKet. Its long-term effects on the human body are unknown, and therefore, it is generally advised for individuals to refrain from consuming CanKet, as is the case for most otherdesigner drugs.
While not much is known about the drug's effects, anecdotal reports offer some insight into them. According to aVICE News interview with one anonymous recreational user,
"it’s worse [thanketamine] but only slightly… The ‘happy’ feeling was lacking a little bit. I find I snort K [ketamine] and a smile forms on my face when it starts kicking in. This was lacking that—I’d just come up and kinda stay in a mundane headspace while feeling wonky."[7]
On online forums, users report conflicting information about its effects, with some users reporting astimulating effect.[8] Most agree that the duration of its effects is four to six hours,[8] much longer thanketamine's duration, which typically is approximately one hour wheninsufflated.[9]
While such anecdotal reports may shed some light on CanKet's effects, it is important to note that these are highly subjective, and individual differences may lead to different users experiencing different effects. Professor Malcom MacLeod, an associate professor at theAustralian National University's research school of chemistry, while speaking on the topic of CanKet, stated, "We don't know much about its effects," observing that users' accounts of the effects vary and are "often quite subjective and [it can be] a bit hard to unravel exactly what’s going on."[7]
Chemically, CanKet is afluorinatedarylcyclohexylamine and aketamine derivative. It is quite similar toketamine structurally but differs in a few ways:
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