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2C-T-17

From Wikipedia, the free encyclopedia

Pharmaceutical compound
2C-T-17
Clinical data
Other names4-sec-Butylthio-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-sec-butylthiophenethylamine; NIMITZ; Nimitz
Routes of
administration
Oral[1]
Drug classSerotonergic psychedelic;Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action10–15 hours[1]
Identifiers
  • 2-(4-butan-2-ylsulfanyl-2,5-dimethoxyphenyl)ethanamine
CAS Number
PubChemCID
ChemSpider
UNII
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC14H23NO2S
Molar mass269.40 g·mol−1
3D model (JSmol)
  • CC(CC)Sc1cc(OC)c(cc1OC)CCN
  • InChI=1S/C14H23NO2S/c1-5-10(2)18-14-9-12(16-3)11(6-7-15)8-13(14)17-4/h8-10H,5-7,15H2,1-4H3 checkY
  • Key:KSZHVRPGICAZOA-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

2C-T-17, also known as4-sec-butylthio-2,5-dimethoxyphenethylamine or asNimitz, is apsychedelic drug of thephenethylamine and2C families.[1] It is takenorally.[1]

2C-T-17 was first described in thescientific literature byAlexander Shulgin and colleagues in 1991.[2] Shortly after this, Shulgin described 2C-T-17 in greater detail in his 1991 bookPiHKAL (Phenethylamines I Have Known and Loved).[1]

Use and effects

[edit]

According toAlexander Shulgin in his bookPiHKAL (Phenethylamines I Have Known and Loved), 2C-T-17's dose range is 60 to 100 mg and itsduration is 10 to 15 hours.[1] Itsonset is 1 hour and peak effects occurred after 3 hours.[1] 2C-T-17 has been described as a "truly heavy psychedelic" but as producing nopsychedelic visuals and very little in the way ofperceptual changes.[1] User reports described it as having pronouncedpsychoactive effects but had difficulty describing exactly what those effects were.[1]

Toxicity

[edit]

Thetoxicity of 2C-T-17 is not well-documented.[citation needed] It is much less potent than 2C-T-7, but it may be expected that at very high doses it would display similar toxicity to that of other phenethylamines of the 2C-T family.[citation needed]

Interactions

[edit]
See also:Psychedelic drug § Interactions, andTrip killer § Serotonergic psychedelic antidotes

Pharmacology

[edit]

Pharmacodynamics

[edit]

Themechanism of action that produces 2C-T-17'shallucinogenic effects has not been specifically established, however it is most likely to result from action as aserotonin5-HT2A receptoragonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.[citation needed]

Chemistry

[edit]

2C-T-17 is the2 carbonhomologue ofAleph-17, which has never been synthesized.[1] The full chemical name is 2-[4-(2-butylthio)-2,5-dimethoxyphenyl]ethanamine.[1] The drug hasstructural properties similar to drugs in the 2C-T series, with the most closely related compounds being2C-T-7 and2C-T-8.[1]

History

[edit]

2C-T-17 was first described in thescientific literature byAlexander Shulgin and colleagues in ajournal article in 1991.[2] Shortly thereafter, it was described in greater detail by Shulgin in his 1991 bookPiHKAL (Phenethylamines I Have Known and Loved).[1]

Society and culture

[edit]

Legal status

[edit]

Canada

[edit]

As of October 31, 2016, 2C-T-17 is a controlled substance (Schedule III) in Canada.[3]

United Kingdom

[edit]

This substance is a Class A drug in theDrugs controlled by the UK Misuse of Drugs Act.[4]

United States

[edit]

2C-T-17 is not illegal, but possession and sales of 2C-T-17 could be prosecuted under theFederal Analog Act in theUnited States because of its structural similarities to2C-T-7.

See also

[edit]

References

[edit]
  1. ^abcdefghijklmShulgin A,Shulgin A (September 1991).PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press.ISBN 0-9630096-0-5.OCLC 25627628.
  2. ^abShulgin AT, Shulgin A, Jacob P (January 1991)."Central nervous system (CNS) activity of two new psychoactive compounds".Journal of Psychoactive Drugs.23 (1):95–96.doi:10.1080/02791072.1991.10472583.eISSN 2159-9777.PMID 1941371. Archived fromthe original on 2025-07-13.
  3. ^"Canada Gazette – Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". 4 May 2016.
  4. ^"UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Retrieved12 March 2014.

External links

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