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| Clinical data | |
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| Other names | 4-Isopropoxy-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-isopropoxyphenethylamine |
| Routes of administration | Oral[1] |
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| Pharmacokinetic data | |
| Duration of action | A few hours[1] |
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| Chemical and physical data | |
| Formula | C13H21NO3 |
| Molar mass | 239.315 g·mol−1 |
| 3D model (JSmol) | |
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2C-O-4, also known as4-isopropoxy-2,5-dimethoxyphenethylamine, is aphenethylamine of the2C family.[1] It is also apositional isomer ofisoproscaline and was probably firstsynthesized byAlexander Shulgin.[1] It produceshallucinogenic orpsychedelic effects.[1] Because of the lowpotency of 2C-O-4, and the inactivity of2C-O, Shulgin felt that the 2C-O series would not be an exciting area for research, and did not pursue any furtheranalogues.[1]
Little is known about thepsychopharmacological effects of 2C-O-4.[1] Based on the one report available in his bookPiHKAL, Shulgin lists the dose of 2C-O-4 as being >60 mg.[1] At 60 mg, thresholdpsychoactive effects occurred.[1] These included awareness of something in the front part of the head,yawning,physiological changes, and a generalexhilaration andexcitement.[1] The effects lasted a few hours and were rated as a +1 on theShulgin Rating Scale.[1] The drug was regarded as remaining to be fully explored.[1]
The toxicity of 2C-O-4 is not known.
Thepharmacology of 2C-O-4 has been studied.[2]
2C-O-4 is in a class of compounds commonly known asphenethylamines, and the systematic chemical name is 2-(4-isopropoxy-2,5-dimethoxyphenyl)ethanamine.
As of October 31, 2016, 2C-O-4 is a controlled substance (Schedule III) in Canada.[3]
2C-O-4 is unscheduled and unregulated in theUnited States; however, because of its close similarity in structure and effects tomescaline and2C-T-7, possession and sale of 2C-O-4 may be subject to prosecution under theFederal Analog Act.
