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2C-F

From Wikipedia, the free encyclopedia
Chemical compound

Pharmaceutical compound
2C-F
Clinical data
Other names4-Fluoro-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-fluorophenethylamine
Routes of
administration
Oral[1]
Drug classSerotonergic psychedelic;Hallucinogen
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Onset of actionUnknown[1]
Duration of actionUnknown[1]
Identifiers
  • 2-(4-fluoro-2,5-dimethoxyphenyl)-1-aminoethane
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC10H14FNO2
Molar mass199.225 g·mol−1
3D model (JSmol)
  • Fc1cc(OC)c(cc1OC)CCN
  • InChI=1S/C10H14FNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3 checkY
  • Key:QAVFEDRVOUKIPM-UHFFFAOYSA-N checkY
  (verify)

2C-F, also known as4-fluoro-2,5-dimethoxyphenethylamine, is apsychedelic drug of thephenethylamine and2C families.[1][2] It is takenorally.[1]

Use effects

[edit]

In his bookPiHKAL (Phenethylamines I Have Known and Loved),Alexander Shulgin lists the dose of 2C-F as greater than 250 mgorally and itsduration as unknown.[1] At a dose of 250 mg, 2C-F produces slight and uncertain effects including possible modestclosed-eye visuals and pleasantlethargy.[1]

Interactions

[edit]
See also:Psychedelic drug § Interactions, andTrip killer § Serotonergic psychedelic antidotes

Pharmacology

[edit]

Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F.[1][3]

Chemistry

[edit]

Properties

[edit]

2C-F may be found as a brownish freebaseoil, or as a white crystalline hydrochloride salt.

Synthesis

[edit]

Thechemical synthesis of 2C-F has been described.[1]

Analogues

[edit]

Analogues of 2C-F include2C-B,2C-I,2C-C,DOF, and25F-NBOMe, among others.[1]

History

[edit]

2C-F was first described in the literature byAlexander Shulgin in his 1991 bookPiHKAL (Phenethylamines I Have Known and Loved).[1]

Society and culture

[edit]

Legal status

[edit]

Canada

[edit]

As of October 31, 2016, 2C-F is a controlled substance (Schedule III) in Canada.[4]

See also

[edit]

References

[edit]
  1. ^abcdefghijkShulgin A,Shulgin A (September 1991).PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press.ISBN 0-9630096-0-5.OCLC 25627628.2C-F Entry inPiHKAL
  2. ^Shulgin A, Manning T, Daley P (2011).The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley:Transform Press.ISBN 978-0-9630096-3-0.
  3. ^Rudin D, Luethi D, Hoener MC, Liechti ME (2022)."Structure-activity Relation of Halogenated 2,5-Dimethoxyamphetamines Compared to their α‑Desmethyl (2C) Analogues".The FASEB Journal.36 (S1).doi:10.1096/fasebj.2022.36.S1.R2121.ISSN 0892-6638.
  4. ^"Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)".Controlled Drugs and Substances Act.150 (9). Government of Canada. 4 May 2016.

External links

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