The brigade fought in thewar in Donbas.[6] On 22 August 2016, its Guards title was removed.[7] On 22 August 2019 by decree ofPresidentVolodymyr Zelensky the official name of the brigade became:28th Separate Mechanized Brigade named after the Knights of theFirst Winter Campaign.[2]
The brigade took part in the defense of Ukraine during theRussian invasion of Ukraine on thesouthern front. According to the chairman of the Public Council at the Odesa Regional State Administration Serhiy Bratchuk, the Russians tried to conduct a maritime and air landing inKobleve [uk] on the Black Sea coast of the Mykolaiv area. As a result of the brigade, the Russians' attempt to land was stopped, and they retreated, losing up to 25 soldiers. Two more saboteurs were detained in the village of Kobleve.[8][9] After the defense of Kobleve, elements of the 28th Brigade took part in thedefense of Voznesensk.[10]
On 10 November, the 28th Brigade reportedly capturedKyselivka.[14] Two days later, on the 12th of November, elements of the brigade were seen enteringKherson as part of the liberation of the city during thesouthern offensive.[citation needed]
Elements of the brigade were also present in thebattle of Bakhmut as of February 2023, with servicemen interviewed byCNN[15] and portrayed byThe New Yorker.[16] Between November 2022 and January 2023, a battalion of the 28th Mechanized Brigade numbering 600 men was reported to had been almost annihilated fighting in a village south ofBakhmut, with around 70 soldiers said to have been encircled and massacred in one incident.[17]
^ab"УКАЗ ПРЕЗИДЕНТА УКРАЇНИ №618/2019" [DECREE OF THE PRESIDENT OF UKRAINE №618 / 2019] (in Ukrainian). President of Ukraine. 22 August 2019. Retrieved7 February 2021.
^"УКАЗ ПРЕЗИДЕНТА УКРАЇНИ № 569/2006" [Decree of the President of Ukraine No. 569/2006] (in Ukrainian). Press Service of the President of Ukraine. 23 June 2006. Archived fromthe original on 22 August 2014. Retrieved31 August 2016.
^"УКАЗ ПРЕЗИДЕНТА УКРАЇНИ №344/2016" [Ukaz of the President of Ukraine No. 344/2016] (in Ukrainian). President of Ukraine. 22 August 2016. Retrieved17 February 2017.