Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

2023 Nobel Prize in Physiology or Medicine

From Wikipedia, the free encyclopedia
An editor has nominated this article for deletion.
You are welcome to participate inthe deletion discussion, which will decidewhether to keep it.
Feel free to improve the article, but do not remove this notice before the discussion is closed. For more information, see theguide to deletion.
Find sources: "2023 Nobel Prize in Physiology or Medicine" – news ·newspapers ·books ·scholar ·JSTOR%5B%5BWikipedia%3AArticles+for+deletion%2F2023+Nobel+Prize+in+Physiology+or+Medicine%5D%5DAFD
Award
The 2023 Nobel Prize in Physiology or Medicine
Katalin Karikó andDrew Weissman
"for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19."
Date2 October 2023 (2023-10-02)
LocationStockholm
CountrySweden
Presented byNobel Assembly at Karolinska Institutet
Reward11 millionSEK (2023)[1]
First award1901
Website2023 Nobel Prize in Physiology or Medicine
← 2022 ·Nobel Prize in Physiology or Medicine· 2024 →

The2023 Nobel Prize in Physiology or Medicine was awarded toKatalin Karikó (born 1955) andDrew Weissman (born 1959) "for their discoveries concerning nucleoside base modifications that enabled the development of effectivemRNA vaccines againstCOVID-19".[2][3]

Laureates

[edit]

Katalin Karikó

[edit]
Main article:Katalin Karikó

Katalin Karikó was born on January 17, 1955, inSzolnok, Hungary.[4] From theUniversity of Szeged, she received aPh.D. in biochemistry in 1982.[5] From 2013 to 2022, she was associated with BioNTech RNA Pharmaceuticals, first as a vice president and promoted to senior vice president in 2019. This company, a division ofBioNTech, commercialized mRNA vaccines at a global scale.

Drew Weissman

[edit]
Main article:Drew Weissman

Drew Weissman was born on September 7, 1959, inLexington, Massachusetts[6] and received aPh.D. in 1987 atBoston University.[7] He started studying RNA at theUniversity of Pennsylvania in 1997,[8] where he met Karikó.[9]

Key publications

[edit]

These are key publications by Karikó and Weissman related to the 2023 prize:[10]

  • Karikó, K., Buckstein, M., Ni, H. andWeissman, D.Suppression of RNA Recognition by Toll-like Receptors: The impact of nucleoside modification and the evolutionary origin of RNA. Immunity23, 165–175 (2005).
  • Karikó, K., Muramatsu, H., Welsh, F.A., Ludwig, J., Kato, H., Akira, S. andWeissman, D.Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. Mol Ther16, 1833–1840 (2008).
  • Anderson, B.R., Muramatsu, H., Nallagatla, S.R., Bevilacqua, P.C., Sansing, L.H.,Weissman, D. andKarikó, K.Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation. Nucleic AcidsRes.38, 5884–5892 (2010).

References

[edit]
  1. ^Burger, Ludwig; Pollard, Niklas (2 October 2023)."Nobel Prize for Medicine goes to Kariko and Weissman, pioneers of COVID vaccine". Reuters.com.Archived from the original on 3 October 2023. Retrieved3 Oct 2023.
  2. ^"The Nobel Prize in Physiology or Medicine 2023".NobelPrize.org.Archived from the original on 2023-10-02. Retrieved2023-10-03.
  3. ^Mueller, Benjamin; Kolata, Gina (2023-10-02)."Nobel Prize Awarded to Covid Vaccine Pioneers".The New York Times.ISSN 0362-4331.Archived from the original on 2023-10-02. Retrieved2023-10-03.
  4. ^Young, Lauren J."Scientists behind mRNA COVID Vaccines Win 2023 Nobel Prize in Physiology or Medicine".Scientific American.Archived from the original on 2023-10-02. Retrieved2023-10-03.
  5. ^Hargittai, Istvan; Hargittai, Magdolna (25 May 2021)."Our science and the Covid-19 pandemic—Katalin Karikó's research idea and her perseverance".Structural Chemistry.32 (4):1353–1356.Bibcode:2021StrCh..32.1353H.doi:10.1007/s11224-021-01797-9.PMC 8143802.PMID 34054260.
  6. ^"Drew Weissman".nobelprize.org. October 2, 2023.Archived from the original on October 2, 2023. RetrievedOctober 2, 2023.
  7. ^"Drew Weissman | Faculty | About Us | Perelman School of Medicine | Perelman School of Medicine at the University of Pennsylvania".www.med.upenn.edu.Archived from the original on July 29, 2010. RetrievedJanuary 8, 2021.
  8. ^"Drew Weissman, MD, PhD profile".www.pennmedicine.org. RetrievedJanuary 8, 2021.
  9. ^"Drew Weissman, l'architecte des vaccins contre le Covid-19".LEFIGARO (in French). December 24, 2020. RetrievedJanuary 8, 2021.
  10. ^Press release: The Nobel Prize in Physiology or Medicine 2023Archived 2023-10-03 at theWayback Machine nobelprize.org

External links

[edit]
1901–1909
1910–1919
1920–1929
1930–1939
1940–1949
1950–1959
1960–1969
1970–1979
1980–1989
1990–1999
2000–2009
2011–2019
2020–present
2023Nobel Prize laureates
Chemistry
Literature (2023)
Peace (2023)
Physics
Physiology or Medicine (2023)
Economic Sciences (2023)
Retrieved from "https://en.wikipedia.org/w/index.php?title=2023_Nobel_Prize_in_Physiology_or_Medicine&oldid=1318388197"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2025 Movatter.jp