| County[20] | Mike Rounds Republican | Daniel Ahlers Democratic | Margin | Total votes |
|---|
| # | % | # | % | # | % |
|---|
| Aurora | 1,002 | 71.32 | 403 | 28.68 | 599 | 42.63 | 1,405 |
|---|
| Beadle | 5,104 | 71.99 | 1,986 | 28.01 | 3,118 | 43.98 | 7,090 |
|---|
| Bennett | 729 | 62.52 | 437 | 37.48 | 292 | 25.04 | 1,166 |
|---|
| Bon Homme | 2,156 | 72.11 | 834 | 27.89 | 1,322 | 44.21 | 2,990 |
|---|
| Brookings | 8,792 | 60.48 | 5,746 | 39.52 | 3,046 | 20.95 | 14,538 |
|---|
| Brown | 11,168 | 64.00 | 6,283 | 36.00 | 4,885 | 27.99 | 17,451 |
|---|
| Brule | 1,735 | 69.65 | 756 | 30.35 | 979 | 39.30 | 2,491 |
|---|
| Buffalo | 223 | 40.92 | 322 | 59.08 | -99 | -18.17 | 545 |
|---|
| Butte | 3,809 | 79.85 | 961 | 20.15 | 2,848 | 59.71 | 4,770 |
|---|
| Campbell | 745 | 85.93 | 122 | 14.07 | 623 | 71.86 | 867 |
|---|
| Charles Mix | 2,542 | 66.88 | 1,259 | 33.12 | 1,283 | 33.75 | 3,801 |
|---|
| Clark | 1,397 | 75.64 | 450 | 24.36 | 947 | 51.27 | 1,847 |
|---|
| Clay | 2,857 | 50.44 | 2,807 | 49.56 | 50 | 0.88 | 5,664 |
|---|
| Codington | 9,479 | 72.33 | 3,626 | 27.67 | 5,853 | 44.66 | 13,105 |
|---|
| Corson | 681 | 53.88 | 583 | 46.12 | 98 | 7.75 | 1,264 |
|---|
| Custer | 3,973 | 72.82 | 1,483 | 27.18 | 2,490 | 45.64 | 5,456 |
|---|
| Davison | 5,893 | 69.88 | 2,540 | 30.12 | 3,353 | 39.76 | 8,433 |
|---|
| Day | 1,895 | 63.93 | 1,069 | 36.07 | 826 | 27.87 | 2,964 |
|---|
| Deuel | 1,714 | 73.19 | 628 | 26.81 | 1,086 | 46.37 | 2,342 |
|---|
| Dewey | 884 | 45.43 | 1,062 | 54.57 | -178 | -9.15 | 1,946 |
|---|
| Douglas | 1,469 | 86.21 | 235 | 13.79 | 1,234 | 72.42 | 1,704 |
|---|
| Edmunds | 1,539 | 77.45 | 448 | 22.55 | 1,091 | 54.91 | 1,987 |
|---|
| Fall River | 3,009 | 75.19 | 993 | 24.81 | 2,016 | 50.37 | 4,002 |
|---|
| Faulk | 975 | 82.07 | 213 | 17.93 | 762 | 64.14 | 1,188 |
|---|
| Grant | 2,723 | 72.63 | 1,026 | 27.37 | 1,697 | 45.27 | 3,749 |
|---|
| Gregory | 1,766 | 78.35 | 488 | 21.65 | 1,278 | 56.70 | 2,254 |
|---|
| Haakon | 1,032 | 90.69 | 106 | 9.31 | 926 | 81.37 | 1,138 |
|---|
| Hamlin | 2,413 | 78.60 | 657 | 21.40 | 1,756 | 57.20 | 3,070 |
|---|
| Hand | 1,480 | 79.66 | 378 | 20.34 | 1,102 | 59.31 | 1,858 |
|---|
| Hanson | 1,796 | 76.10 | 564 | 23.90 | 1,232 | 52.20 | 2,360 |
|---|
| Harding | 727 | 90.88 | 73 | 9.13 | 654 | 81.75 | 800 |
|---|
| Hughes | 6,217 | 70.95 | 2,546 | 29.05 | 3,671 | 41.89 | 8,763 |
|---|
| Hutchinson | 2,982 | 79.44 | 772 | 20.56 | 2,210 | 58.87 | 3,754 |
|---|
| Hyde | 568 | 79.89 | 143 | 20.11 | 425 | 59.77 | 711 |
|---|
| Jackson | 756 | 67.92 | 357 | 32.08 | 399 | 35.85 | 1,113 |
|---|
| Jerauld | 720 | 72.22 | 277 | 27.78 | 443 | 44.43 | 997 |
|---|
| Jones | 497 | 83.39 | 99 | 16.61 | 398 | 66.78 | 596 |
|---|
| Kingsbury | 1,970 | 70.89 | 809 | 29.11 | 1,161 | 41.78 | 2,779 |
|---|
| Lake | 3,816 | 64.84 | 2,069 | 35.16 | 1,747 | 29.69 | 5,885 |
|---|
| Lawrence | 9,385 | 68.29 | 4,358 | 31.71 | 5,027 | 36.58 | 13,743 |
|---|
| Lincoln | 21,221 | 65.83 | 11,013 | 34.17 | 10,208 | 31.67 | 32,234 |
|---|
| Lyman | 1,066 | 66.67 | 533 | 33.33 | 533 | 33.33 | 1,599 |
|---|
| Marshall | 1,334 | 61.00 | 853 | 39.00 | 481 | 21.99 | 2,187 |
|---|
| McCook | 2,072 | 71.28 | 835 | 28.72 | 1,237 | 42.55 | 2,907 |
|---|
| McPherson | 1,086 | 82.21 | 235 | 17.79 | 851 | 64.42 | 1,321 |
|---|
| Meade | 10,355 | 76.53 | 3,176 | 23.47 | 7,179 | 53.06 | 13,531 |
|---|
| Mellette | 468 | 60.70 | 303 | 39.30 | 165 | 21.40 | 771 |
|---|
| Miner | 807 | 70.42 | 339 | 29.58 | 468 | 40.84 | 1,146 |
|---|
| Minnehaha | 52,773 | 57.63 | 38,799 | 42.37 | 13,974 | 15.26 | 91,572 |
|---|
| Moody | 1,877 | 58.29 | 1,343 | 41.71 | 534 | 16.58 | 3,220 |
|---|
| Oglala Lakota | 510 | 15.93 | 2,691 | 84.07 | -2,181 | -68.13 | 3,201 |
|---|
| Pennington | 37,694 | 66.27 | 19,184 | 33.73 | 18,510 | 32.54 | 56,878 |
|---|
| Perkins | 1,395 | 84.85 | 249 | 15.15 | 1,146 | 69.71 | 1,644 |
|---|
| Potter | 1,160 | 83.82 | 224 | 16.18 | 936 | 67.63 | 1,384 |
|---|
| Roberts | 2,529 | 58.87 | 1,767 | 41.13 | 762 | 17.74 | 4,296 |
|---|
| Sanborn | 898 | 76.17 | 281 | 23.83 | 617 | 52.33 | 1,179 |
|---|
| Spink | 2,178 | 68.84 | 986 | 31.16 | 1,192 | 37.67 | 3,164 |
|---|
| Stanley | 1,274 | 77.12 | 378 | 22.88 | 896 | 54.24 | 1,652 |
|---|
| Sully | 759 | 81.88 | 168 | 18.12 | 591 | 63.75 | 927 |
|---|
| Todd | 706 | 28.22 | 1,796 | 71.78 | -1,090 | -43.57 | 2,502 |
|---|
| Tripp | 2,188 | 81.34 | 502 | 18.66 | 1,686 | 62.68 | 2,690 |
|---|
| Turner | 3,416 | 75.21 | 1,126 | 24.79 | 2,290 | 50.42 | 4,542 |
|---|
| Union | 6,364 | 72.56 | 2,407 | 27.44 | 3,957 | 45.11 | 8,771 |
|---|
| Walworth | 2,040 | 79.53 | 525 | 20.47 | 1,515 | 59.06 | 2,565 |
|---|
| Yankton | 6,994 | 64.51 | 3,848 | 35.49 | 3,146 | 29.02 | 10,842 |
|---|
| Ziebach | 450 | 49.56 | 458 | 50.44 | -8 | -0.88 | 908 |
|---|
| Totals | 276,232 | 65.74 | 143,987 | 34.26 | 132,245 | 31.47 | 420,219 |
|---|
Counties that flipped from Democratic to Republican |