Roger Federer was the defending champion, but lost in the quarterfinals to Berdych. This marked the first time since2002 that Federer did not reach the final, and the second successive major where Federer was defeated at the quarterfinal stage, having previously been on a record run of 23 successive major semifinals. Federer's loss, along with those ofLleyton Hewitt andAndy Roddick, both in the fourth round, guaranteed a first-time Wimbledon finalist from the top half of the draw.
Berdych was the first Czech man to reach the final sinceIvan Lendl in1987. For the first time, there were no English players in the Wimbledon men's singles competition, though Great Britain was represented by two players from Scotland: fourth seedAndy Murray and wildcardJamie Baker.[3]
Thefirst-round match betweenJohn Isner andNicolas Mahut set a new record for thelongest tennis match in history (in both time and total of games), as well as many other records due to its length. Isner won the match, taking the final set 70–68 after a total of 11 hours and 5 minutes of play across three days.[4] Coincidentally, the two faced each other again in the first round the following year, with Isner taking that match in straight sets, 7–6(7–4), 6–2, 7–6(8–6).
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Ernests Gulbis withdrew due to a muscle tear in his right thigh. He was replaced in the draw by the highest-ranked non-seeded playerPhilipp Petzschner, who became the #33 seed.