The1980 Clemson Tigers football team was anAmerican football team that representedClemson University in theAtlantic Coast Conference (ACC) during the1980 NCAA Division I-A football season. In its third season under head coachDanny Ford, the team compiled a 6–5 record (2–4 against conference opponents), tied for fourth place in the ACC, and was outscored by a total of 222 to 217.^[1][2] The team won the 100th ACC game in Clemson history on November 1 and played its home games atMemorial Stadium inClemson, South Carolina.

Lee Nanney and Willie Underwood were the team captains. The team's statistical leaders included quarterbackHomer Jordan with 1,311 passing yards, Chuck McSwain with 544 rushing yards,Perry Tuttle with 915 receiving yards, and placekickerObed Ariri with 87 points scored (23 field goals, 18 extra points).^[3]

Date	Time	Opponent	Site	Result	Attendance	Source
September 13	1:00 p.m.	Rice*	Memorial Stadium Clemson, SC	W 19–3	60,361	[4]
September 20	1:30 p.m.	at No. 10Georgia*	Sanford Stadium Athens, GA (rivalry)	L 16–20	61,200	[5]
September 27	1:00 p.m.	Western Carolina*	Memorial Stadium Clemson, SC	W 17–10	58,490	[6]
October 4	1:00 p.m.	Virginia Tech*	Memorial Stadium Clemson, SC	W 13–10	64,558	[7]
October 11	1:30 p.m.	atVirginia	Scott Stadium Charlottesville, VA	W 27–24	32,443	[8]
October 18	1:00 p.m.	Duke	Memorial Stadium Clemson, SC	L 17–34	59,873	[9]
October 25	1:00 p.m.	atNC State	Carter–Finley Stadium Raleigh, NC (rivalry)	L 20–24	44,400	[10]
November 1	1:00 p.m.	atWake Forest	Groves Stadium Winston-Salem, NC	W 35–33	28,200	[11]
November 8	1:00 p.m.	No. 14North Carolina	Memorial Stadium Clemson, SC	L 19–24	62,500	[12]
November 15	1:20 p.m.	atMaryland	Byrd Stadium College Park, MD	L 7–34	32,650	[13]
November 22	1:00 p.m.	No. 19South Carolina*	Memorial Stadium Clemson, SC (rivalry)	W 27–6	64,200	[14]
*Non-conference game Homecoming Rankings fromAP Poll released prior to the game All times are inEastern time

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• 1980 Atlantic Coast Conference football season
• Clemson Tigers football seasons
• 1980 in sports in South Carolina

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