The1978 Missouri Tigers football team represented theUniversity of Missouri during the1978 NCAA Division I-A football season as a member of theBig Eight Conference (Big 8). The team was led by head coachWarren Powers, in his first year, and they played their home games atFaurot Field inColumbia, Missouri. They finished the season with a record of eight wins and four losses (8–4, 4–3 Big 8) and with a victory overLSU in theLiberty Bowl.

Date	Opponent	Rank	Site	TV	Result	Attendance	Source
September 9	at No. 5Notre Dame*		Notre Dame Stadium Notre Dame, IN		W 3–0	59,075	[1]
September 16	No. 1Alabama*	No. 11	Faurot Field Columbia, MO		L 20–38	73,655	[2]
September 23	Ole Miss*	No. 17	Faurot Field Columbia, MO		W 45–14	60,287	[3]
September 30	at No. 1Oklahoma	No. 14	Oklahoma Memorial Stadium Norman, OK (rivalry)		L 23–45	72,371	[4]
October 7	Illinois*		Faurot Field Columbia, MO		W 45–3	62,062	[5]
October 14	No. 20Iowa State	No. 19	Faurot Field Columbia, MO (rivalry)		W 26–13	63,106	[6]
October 21	atKansas State	No. 13	KSU Stadium Manhattan, KS		W 56–14	24,500	[7]
October 28	Colorado	No. 13	Faurot Field Columbia, MO	ABC	L 27–28	71,096	[8]
November 4	atOklahoma State		Lewis Field Stillwater, OK		L 20–35	47,750	[9]
November 11	Kansas		Faurot Field Columbia, MO (Border War)		W 48–0	64,453	[10]
November 18	at No. 2Nebraska		Memorial Stadium Lincoln, NE (rivalry)		W 35–31	75,850	[11]
December 23	vs.LSU*	No. 18	Liberty Bowl Memorial Stadium Memphis, TN (Liberty Bowl)	ABC	W 20–15	53,064	[12]
*Non-conference game Homecoming Rankings fromAP Poll released prior to the game

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• Warren Powers,Walter Camp Coach of the Year

• 1978 Big Eight Conference football season
• Missouri Tigers football seasons
• Liberty Bowl champion seasons
• 1978 in sports in Missouri

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