The1941 United States Senate special election in Mississippi was held on September 29 to complete the unexpired term of SenatorPat Harrison. Interim SenatorJames Eastland did not run for a full term in office. In the election, U.S. RepresentativeWall Doxey narrowly defeated his House colleagueRoss A. Collins.
Four-term Democratic senatorPat Harrison died June 22, 1941. GovernorPaul B. Johnson Sr. appointed Democratic planter and former state representativeJames Eastland on June 30 to fill the vacant seat until a successor could be duly elected. Eastland was appointed after his father, Woods Eastland, declined and on the condition that he would not run in the special election to complete the term.[citation needed]