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| Clinical data | |
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| Other names | 1-Testo; 1-T; δ1-Dihydrotestosterone; δ1-DHT; Dihydroboldenone |
| Drug class | Androgen;Anabolic steroid |
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| Pharmacokinetic data | |
| Metabolism | Liver |
| Excretion | Urine |
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| ECHA InfoCard | 100.164.058 |
| Chemical and physical data | |
| Formula | C19H28O2 |
| Molar mass | 288.431 g·mol−1 |
| 3D model (JSmol) | |
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1-Testosterone (abbreviated and nicknamed as1-Testo,1-T), also known asδ1-dihydrotestosterone (δ1-DHT), as well asdihydroboldenone, is asyntheticanabolic–androgenic steroid (AAS) and a5α-reducedderivative ofboldenone (Δ1-testosterone). It differs fromtestosterone by having a 1(2)-double bond instead of a 4(5)-double bond in itsA ring.[1] It was legally sold online in theUnited States until 2005, when it was reclassified as aSchedule IIIdrug.
A 2006 study determined that 1-testosterone has a high androgenic and anabolic potency even without being metabolized, so it can be characterized as a typical anabolic steroid. 1-Testosterone binds in a manner that is highly selective to theandrogen receptor (AR) and has a high potency to stimulate AR-dependenttransactivation.In vivo, an equimolar dose of 1-testosterone has the same potency to stimulate the growth of theprostate, theseminal vesicles and the androgen-sensitivelevator animuscle as the reference anabolic steroidtestosterone propionate, but, unlike testosterone propionate, 1-testosterone also increasesliver weight.[2]
1-Testosterone, IUPAC name 17β-hydroxy-5α-androst-1-en-3-one, also known as 4,5α-dihydro-δ1-testosterone (Δ1-DHT) or as 5α-androst-1-en-17β-ol-3-one, is asyntheticandrostanesteroid and aderivative ofdihydrotestosterone (DHT).
Twoprohormones of 1-testosterone are1-androstenediol and1-androstenedione, the latter of which may besynthesized fromstanolone acetate.[3]
Doping with 1-testosterone can be detected in urine samples usinggas chromatography.[4]
