Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

5-Androstenedione

From Wikipedia, the free encyclopedia
(Redirected fromΔ5-Androstenedione)
Chemical compound
Pharmaceutical compound
5-Androstenedione
Clinical data
Other namesAndrost-5-ene-3,17-dione; Δ5-Androstenedione; NSC-12873
Routes of
administration		Oral
Identifiers
  • (8R,9S,10R,13S,14S)-10,13-Dimethyl-2,4,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
Chemical and physical data
FormulaC19H26O2
Molar mass286.415 g·mol−1
3D model (JSmol)
  • C[C@]12CC[C@H]3[C@@H](CC=C4CC(=O)CC[C@]34C)[C@@H]1CCC2=O
  • InChI=InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,14-16H,4-11H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1 checkY
  • Key:SQGZFRITSMYKRH-QAGGRKNESA-N checkY

5-Androstenedione, also known asandrost-5-ene-3,17-dione, is aprohormone oftestosterone. TheWorld Anti-Doping Agency prohibits its use inathletes. In theUnited States, it is acontrolled substance.

5-Androstenedione is structurally similar to4-androstenedione, with the exception of the position of a carbon-carbondouble bond.

4-Androstenedione isnaturally produced in the body by theadrenal glands andgonads. In addition totestosterone, it is also aprecursor ofestrone andestradiol.[1][2]

5-Androstenedione is on theWorld Anti-Doping Agency's list of prohibited substances,[3] and is therefore banned from use in most major sports.

References

[edit]
  1. ^Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, et al. (January 2011)."DrugBank 3.0: a comprehensive resource for 'omics' research on drugs".Nucleic Acids Research.39 (Database issue):D1035 –D1041.doi:10.1093/nar/gkq1126.PMC 3013709.PMID 21059682.
  2. ^Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, et al. (January 2008)."DrugBank: a knowledgebase for drugs, drug actions and drug targets".Nucleic Acids Research.36 (Database issue):D901 –D906.doi:10.1093/nar/gkm958.PMC 2238889.PMID 18048412.
  3. ^"The World Anti-Doping Code: The 2020 Prohibited List"(PDF).World Anti-Doping Agency. Retrieved2019-12-28.

External links

[edit]
ARTooltip Androgen receptor
Agonists
SARMsTooltip Selective androgen receptor modulator
Antagonists
GPRC6A
Agonists
CARTooltip Constitutive androstane receptor
PXRTooltip Pregnane X receptor

This article about anAndrogen is astub. You can help Wikipedia byexpanding it.

Stub icon

Thisdrug article relating to thegenito-urinary system is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=5-Androstenedione&oldid=1308580091"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2025 Movatter.jp