| Clinical data | |
|---|---|
| Other names | alpha-Zearalenol;trans-Zearalenol; 2,4-Dihydroxy-6-(6α,10-dihydroxy-trans-1-undecenyl)benzoic acid μ-lactone |
| Identifiers | |
| |
| CAS Number | |
| PubChemCID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard(EPA) | |
| ECHA InfoCard | 100.264.264 |
| Chemical and physical data | |
| Formula | C18H24O5 |
| Molar mass | 320.385 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
α-Zearalenol is anonsteroidalestrogen of theresorcylic acid lactone group related tomycoestrogens found inFusarium spp.[1] It is the α-epimer ofβ-zearalenol.[2] Along with β-zearalenol, it is a majormetabolite ofzearalenone formed mainly in theliver but also to a lesser extent in theintestines duringfirst-pass metabolism.[2][3] A relatively low proportion of β-zearalenol is metabolized from zearalenone compared to α-zearalenol in humans.[3] α-Zearalenol is about three to four times more potent as an estrogen relative to zearalenone.[1]