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Yimon Aye

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American biochemist and molecular biologist
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(May 2021) (Learn how and when to remove this message)
Associate professor
Yimon Aye
ရည်မွန်အေး
Yimon Aye in 2018
Born12 July 1980 (1980-07-12) (age 45)
CitizenshipUS-American
Known forElectrophile signaling
Nucleotide signaling pathways
RelativesSoe Thein (father)
Academic background
EducationChemistry
Alma materUniversity of Oxford
Harvard University
Massachusetts Institute of Technology
Doctoral advisorDavid A. Evans
Other advisorJoAnne Stubbe
Academic work
DisciplineBiology
Sub-disciplineMolecular Biology
InstitutionsUniversity of Oxford
Main interestsSynthetic Methodology
Chemical Biology
Biochemistry
Biophysics
Molecular Biology
Cell Biology
Websitehttps://www.chem.ox.ac.uk/people/yimon-aye

Yimon Aye (Burmese:ရည်မွန်အေး; born 12 July 1980[1] inBurma) is an Americanchemist andmolecular biologist. Currently she is a professor of chemistry & chemical biology atUniversity of Oxford.[2]

Career

[edit]

Aye spent her early life inBurma. She completed her undergraduate studies inchemistry at theUniversity of Oxford and obtained her master's degree in 2004.[3] She joinedHarvard University to studysynthetic organic chemistry withDavid A. Evans, achieving herPhD in 2009.[4] She then moved toMassachusetts Institute of Technology as aDamon Runyon Cancer Research Foundation fellow to work withJoAnne Stubbe. There she performed research into the regulatory mechanisms ofribonucleotide reductase.[5]

In 2012, she started as an assistant professor atCornell University, where she began her work on redox-dependentcell signaling andgenome maintenance pathways. During this time, she developed REX technologies, new methods to facilitate the study of unconventional electrophile-regulated stress signaling paradigms.[6][7] REX technologies were one of the first approaches to forge direct links between upstream protein alteration by a reactive molecule and downstream responses.[4] From August 2018 to August 2024 she was an associate professor of chemistry atEPFL.[8]

Since September 2024 she's leading the Aye Lab atUniversity of Oxford.[2]

Awards

[edit]

Aye was awarded the NSF CAREER award and Beckman Young Investigator award in 2014,[9][10] the 2020 Eli Lilly Award in Biological Chemistry,[11] the 2022 Tetrahedron Young Investigator Award,[12] and the Klaus Grohe Prize 2024.[13]

Personal life

[edit]

Yimon Aye's fatherSoe Thein is a former Commander-in-Chief of theMyanmar Navy.[14] She has a brother and a sister.[1]

References

[edit]
  1. ^ab"Council Decision 2012/98/CFSP of 17 February 2012 amending Decision 2010/232/CFSP renewing restrictive measures against Burma/Myanmar".Official Journal of the European Union. Retrieved2022-08-05.
  2. ^ab"Yimon Aye".Department of Chemistry, University of Oxford. Retrieved2024-10-10.
  3. ^admin (2018-01-12)."Interview with Dr.Yimon Aye Assistant Professor of Cornell University".Myanmar Insider. Retrieved2020-09-21.
  4. ^ab"2017 WCC Rising Star Dr. Yimon Aye – Corn... | ACS Network".communities.acs.org. Retrieved2020-09-21.
  5. ^"JoAnne Stubbe Research Group - MIT".web.mit.edu. Retrieved2020-09-21.
  6. ^Poganik, Jesse R.; Long, Marcus J. C.; Aye, Yimon (2019-02-11)."Interrogating Precision Electrophile Signaling".Trends in Biochemical Sciences.44 (4):380–381.doi:10.1016/j.tibs.2019.01.006.ISSN 0968-0004.PMC 6462755.PMID 30765181.
  7. ^Long, Marcus J.C.; Urul, Daniel A.; Aye, Yimon (2020), "REX technologies for profiling and decoding the electrophile signaling axes mediated by Rosetta Stone proteins",Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C, Methods in Enzymology, vol. 633, Elsevier, pp. 203–230,doi:10.1016/bs.mie.2019.02.039,ISBN 978-0-12-819128-6,PMC 7027669,PMID 32046846
  8. ^"15 new professors appointed at the two Federal Institutes of Technology".www.admin.ch. Retrieved2022-02-11.
  9. ^"NSF Award Search: Award # 1351400 - CAREER: A Chemical Technology to Define Target-Specific Bioreactivity: Integrating Research and Education at the Crossroads of Chemistry and Biology".www.nsf.gov. Retrieved2025-03-17.
  10. ^"Yimon Aye is a Beckman Young Investigator | Cornell Chronicle".news.cornell.edu. Retrieved2025-03-17.
  11. ^Papageorgiou, Nik."Yimon Aye wins 2020 Eli Lilly Award".News EPFL. Retrieved2024-03-17.
  12. ^Papageorgiou, Nik."Yimon Aye wins Tetrahedron Young Investigator Award".News EPFL. Retrieved2025-03-17.
  13. ^Goedecke, Catharina (2024-09-01)."Klaus Grohe Prize 2024 for Yimon Aye".ChemistryViews. Retrieved2025-03-17.
  14. ^"ပြည်ခိုင်ဖြိုးကိုယ်စားလှယ်လောင်း ဝန်ကြီးဟောင်းများပိုင်ဆိုင်သည့် ကုမ္ပဏီများ".Myanmar NOW (in Burmese). 23 September 2020. Retrieved2022-02-17.
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