Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Stanley Cohen (biochemist)

From Wikipedia, the free encyclopedia
American biochemist (1922–2020)
Stanley Cohen
Stanley Cohenc. 1986
Born(1922-11-17)November 17, 1922
DiedFebruary 5, 2020(2020-02-05) (aged 97)
EducationUniversity of Michigan
Oberlin College
Brooklyn College
Known forNerve growth factor
AwardsRosenstiel Award(1981)
Louisa Gross Horwitz Prize(1983)
Albert Lasker Award for Basic Medical Research(1986)
Nobel Prize in Physiology or Medicine(1986)
Franklin Medal(1987)
Scientific career
FieldsBiochemistry
InstitutionsVanderbilt University (1959–1999)
Washington University in St. Louis (1953–1959)
ThesisThe Nitrogenous Metabolism of the Earthworm (1949)
Doctoral advisorHoward B. Lewis[1][2]

Stanley Cohen (November 17, 1922 – February 5, 2020) was an American biochemist who, along withRita Levi-Montalcini, was awarded theNobel Prize inPhysiology or Medicine in 1986 for the isolation ofnerve growth factor and the discovery ofepidermal growth factor.

Early life and education

[edit]

Cohen was born in Brooklyn, New York, on November 17, 1922. He was the son of Fannie (née Feitel) and Louis Cohen, a tailor.[3][4] His parents wereJewish immigrants.[5] Cohen received hisbachelor's degree in 1943 fromBrooklyn College, where he had double-majored inchemistry andbiology. After working as abacteriologist at a milk processing plant to earn money, he received hisMaster of Arts inzoology fromOberlin College in 1945. He earned adoctorate from the department of biochemistry about the metabolism of earthworms at theUniversity of Michigan in 1948.[6]

Career

[edit]

His first academic employment was at the University of Colorado studying the metabolism of premature babies. In 1952 he moved toWashington University in St. Louis, working first in the department of radiology, learning isotope methodology, and then in the department of zoology. Working withRita Levi-Montalcini, he isolated nerve growth factor. He later isolated a protein that could accelerate incisor eruption and eyelid opening in newborn mice,[7] which was renamed epidermal growth factor.[8] He continued research on cellular growth factors after joining the faculty ofVanderbilt University School of Medicine in 1959.[6]

Cohen in 2007

In 1999, Cohen retired from Vanderbilt University.[9] He died in February 2020 at the age of 97.[10][11]

Awards and legacy

[edit]

Cohen received theLouisa Gross Horwitz Prize fromColumbia University together with Rita Levi-Montalcini in 1983, theNobel Prize inPhysiology or Medicine in 1986 for the isolation ofnerve growth factor and the discovery ofepidermal growth factor and theNational Medal of Science in 1986.[12][13][14][15]His research on cellular growth factors has proven fundamental to understanding the development ofcancer and designing anti-cancer drugs.

His Scopush-index value was 82 as of March 2022.[16]

See also

[edit]

References

[edit]
  1. ^Cohen, S.; Lewis, H. B. (1949)."The nitrogenous metabolism of the earthworm (Lumbricus terrestris)".The Journal of Biological Chemistry.180 (1):79–91.doi:10.1016/S0021-9258(18)56725-9.PMID 18133376.
  2. ^Cohen, S.; Lewis, H. B. (1950)."The nitrogenous metabolism of the earthworm (Lumbricus terrestric). II. Arginase and urea synthesis".The Journal of Biological Chemistry.184 (2):479–484.doi:10.1016/S0021-9258(19)50977-2.PMID 15428427.
  3. ^Stanley Cohen Biography.Archived from the original on 17 November 2017. Retrieved6 May 2018 – via www.bookrags.com.
  4. ^Sleeman, Elizabeth, ed. (2003).The international who's who 2004 (67th ed.). London: Europa. p. 339.ISBN 978-1857432176. Retrieved4 May 2016.
  5. ^Fox, Daniel M.; Meldrum, Marcia; Rezak, Ira (2019-01-15).Nobel Laureates in Medicine or Physiology: A Biographical Dictionary. Routledge.ISBN 9780429665035.
  6. ^ab"The Nobel Prize in Physiology or Medicine 1986".NobelPrize.org. Retrieved2024-02-17.
  7. ^Watts, Geoff (March 2020)."Stanley Cohen".The Lancet.395 (10227): 864.doi:10.1016/S0140-6736(20)30550-X.
  8. ^Carpenter, G.;Cohen, S. (1979). "Epidermal Growth Factor".Annual Review of Biochemistry.48:193–216.doi:10.1146/annurev.bi.48.070179.001205.PMID 382984.
  9. ^"Cohen's visit brings alive wonder, power of science (12/7/07)".www.mc.vanderbilt.edu. Archived fromthe original on 2020-07-28. Retrieved2019-11-17.
  10. ^"Biochemist and Nobel Prize winner Stanley Cohen dies in Nashville at age 97".
  11. ^Glaser, Vicki (7 February 2020)."Stanley Cohen, Nobelist, Dies at 97; Made Breakthrough on Cell Growth".The New York Times.
  12. ^Cohen, Stanley (1993)."Epidermal Growth Factor"(PDF). In Tore Frängsmyr; Jan Lindsten (eds.).Nobel Lectures, Physiology or Medicine 1981–1990. Singapore: World Scientific Publishing Co.ISBN 978-981-02-0793-9.Archived(PDF) from the original on 2010-12-15. Cohen's Nobel Lecture.
  13. ^Raju, T. N. (2000). "The Nobel chronicles. 1986: Stanley Cohen Cohen (b 1922); Rita Levi-Montalcini (b 1909)".Lancet.355 (9202): 506.doi:10.1016/S0140-6736(00)82069-3.PMID 10841166.S2CID 54340580.
  14. ^Shampo, M. A.; Kyle, R. A. (1999)."Stanley Cohen—Nobel Laureate for Growth Factor".Mayo Clinic Proceedings.74 (6): 600.doi:10.4065/74.6.600.PMID 10377936.
  15. ^Weltman, J. K. (1987). "The 1986 Nobel Prize for Physiology or Medicine awarded for discovery of growth factors: Rita Levi-Montalcini, M.D., and Stanley Cohen, Ph.D".New England and Regional Allergy Proceedings.8 (1):47–48.doi:10.2500/108854187779045385.PMID 3302667.
  16. ^"Cohen, Stanley N." Retrieved1 March 2020.

External links

[edit]
1901–1909
1910–1919
1920–1929
1930–1939
1940–1949
1950–1959
1960–1969
1970–1979
1980–1989
1990–1999
2000–2009
2011–2019
2020–present
1986Nobel Prize laureates
Chemistry
Literature (1986)
Peace
Physics
Physiology or Medicine
Economic Sciences
Behavioral and social science
1960s
1980s
1990s
2000s
2010s
2020s
Biological sciences
1960s
1970s
1980s
1990s
2000s
2010s
2020s
Chemistry
1960s
1980s
1990s
2000s
2010s
Engineering sciences
1960s
1970s
1980s
1990s
2000s
2010s
2020s
Mathematical, statistical, and computer sciences
1960s
1970s
1980s
1990s
2000s
2010s
2020s
Physical sciences
1960s
1970s
1980s
1990s
2000s
2010s
2020s
International
National
Other
Retrieved from "https://en.wikipedia.org/w/index.php?title=Stanley_Cohen_(biochemist)&oldid=1336042680"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2026 Movatter.jp