Amongblack garden ants (Lasius niger), the lifespan ofqueens is an order of magnitude greater than that of workers despite no systematic nucleotide sequence difference between them.[6] TheSOD3 gene was found to be the most differentially over-expressed gene in the brains of queen vs worker ants. This finding raises the possibility that SOD3 antioxidant activity plays a key role in the striking longevity of social insect queens.[6]
^abLucas ER, Keller L. Elevated expression of ageing and immunity genes in queens of the black garden ant. Exp Gerontol. 2018 Jul 15;108:92-98. doi: 10.1016/j.exger.2018.03.020. Epub 2018 Apr 3. PMID: 29625209
Adachi T, Ohta H, Yamada H, Futenma A, Kato K, Hirano K (November 1992). "Quantitative analysis of extracellular-superoxide dismutase in serum and urine by ELISA with monoclonal antibody".Clinica Chimica Acta; International Journal of Clinical Chemistry.212 (3):89–102.doi:10.1016/0009-8981(92)90176-Q.PMID1477980.
Adachi T, Ohta H, Hayashi K, Hirano K, Marklund SL (September 1992). "The site of nonenzymic glycation of human extracellular-superoxide dismutase in vitro".Free Radical Biology & Medicine.13 (3):205–10.doi:10.1016/0891-5849(92)90016-A.PMID1505778.
Hendrickson DJ, Fisher JH, Jones C, Ho YS (December 1990). "Regional localization of human extracellular superoxide dismutase gene to 4pter-q21".Genomics.8 (4):736–8.doi:10.1016/0888-7543(90)90264-U.PMID2276747.
Yamamoto M, Hara H, Adachi T (August 2002). "The expression of extracellular-superoxide dismutase is increased by lysophosphatidylcholine in human monocytic U937 cells".Atherosclerosis.163 (2):223–8.doi:10.1016/S0021-9150(02)00007-2.PMID12052468.
