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SLC35C2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
SLC35C2
Identifiers
AliasesSLC35C2, BA394O2.1, C20orf5, CGI-15, OVCOV1, solute carrier family 35 member C2
External IDsMGI:2385166;HomoloGene:6581;GeneCards:SLC35C2;OMA:SLC35C2 - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for SLC35C2
Genomic location for SLC35C2
Band20q13.12Start46,345,980bp[1]
End46,364,458bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for SLC35C2
Genomic location for SLC35C2
Band2 H3|2 85.53 cMStart165,118,474bp[2]
End165,129,789bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tendon of biceps brachii

  • right uterine tube

  • granulocyte

  • left lobe of thyroid gland

  • right lobe of thyroid gland

  • stromal cell of endometrium

  • right adrenal cortex

  • left adrenal cortex

  • right ovary

  • minor salivary glands
Top expressed in
  • lacrimal gland

  • granulocyte

  • duodenum

  • right kidney

  • dentate gyrus of hippocampal formation granule cell

  • yolk sac

  • jejunum

  • superior frontal gyrus

  • primary visual cortex

  • muscle of thigh
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51006

228875

Ensembl

ENSG00000080189

ENSMUSG00000017664

UniProt

Q9NQQ7

Q8VCX2

RefSeq (mRNA)
NM_001281457
NM_001281458
NM_001281459
NM_001281460
NM_015945

NM_173073
NM_173179

NM_001252573
NM_001252574
NM_001252575
NM_144893
NM_001363015

NM_001363016

RefSeq (protein)
NP_001268386
NP_001268387
NP_001268388
NP_001268389
NP_057029

NP_775096
NP_775271

NP_001239502
NP_001239503
NP_001239504
NP_659142
NP_001349944

NP_001349945

Location (UCSC)Chr 20: 46.35 – 46.36 MbChr 2: 165.12 – 165.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 35 member C2 is aprotein that in humans is encoded by theSLC35C2gene.[5][6][7]

Oxygenation levels play an important role in the regulation of cellular invasiveness which occurs during early implantation when thetrophoblast cells invade theuterus as well as duringtumour progression andmetastasis. This gene, which is regulated byoxygen tension, is induced inhypoxic trophoblast cells and isoverexpressed inovarian cancer. Two proteinisoforms are encoded by transcript variants of this gene.[7]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000080189Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000017664Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000)."Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics".Genome Res.10 (5):703–13.doi:10.1101/gr.10.5.703.PMC 310876.PMID 10810093.
  6. ^Fossey SC, Mychaleckyj JC, Pendleton JK, Snyder JR, Bensen JT, Hirakawa S, Rich SS, Freedman BI, Bowden DW (Sep 2001). "A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20".Genomics.76 (1–3):45–57.doi:10.1006/geno.2001.6584.PMID 11549316.
  7. ^ab"Entrez Gene: SLC35C2 solute carrier family 35, member C2".

Further reading

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