| Pilonidal disease | |
|---|---|
| Other names | Pilonidal cyst, pilonidal abscess, pilonidal sinus, sacrococcygeal cyst / fistula |
 | |
| Acute pilonidal disease (abscess) in the uppergluteal cleft | |
| Specialty | General surgery,colorectal surgery |
| Symptoms | Pain, swelling, redness, drainage of fluid[1] |
| Usual onset | Young adulthood[2] |
| Causes | Ingrown hair in the natal cleft |
| Risk factors | Obesity, family history, greater amounts of hair (hirsutism), not enough exercise[2] |
| Diagnostic method | Based on symptoms and examination[2] |
| Differential diagnosis | Hidradenitis suppurativa,perianal abscess,folliculitis[2] |
| Prevention | Shaving the area[1] |
| Treatment | Incision and drainage,[2]surgical removal |
| Frequency | 3 per 10,000 per year[2] |
Pilonidal disease is a type of skin infection that typically occurs as a cystbetween the cheeks of the buttocks and often at the upper end.[1][3] Symptoms may include pain, swelling, and redness.[1] There may also be drainage of fluid, but rarely a fever.[1][2]
Risk factors includeobesity, family history, prolonged sitting, greater amounts of hair, and not enough exercise.[2] The underlying mechanism is believed to involve amechanical process where hair and skin debris get sucked into the subcutaneous tissues through skin openings called pits.[2] Diagnosis is based on symptoms and examination.[2]
If there is an infection, treatment is generally byincision and drainage just off the midline.[1][2]Shaving the area and laser hair removal may prevent recurrence.[1][4] More extensive surgery may be required if the disease recurs.[1]Antibiotics are usually not needed.[2] Without treatment, the condition may remain long-term.[1]
About 3 per 10,000 people per year are affected, and it occurs more often in males than females.[2] Young adults are most commonly affected.[2] The termpilonidal means 'nest of hair'.[1] The condition was first described in 1833.[1]
Pilonidal cysts can be itchy and often very painful, and typically occur between the ages of 15 and 35.[5] Although usually found near thecoccyx, the condition can also affect thenavel,armpit, the cheek,[6] or thegenital region,[7] though these locations are much rarer.
Signs and symptoms may include:[8]
Some people with a pilonidal cyst will beasymptomatic.[9]
Pilonidal sinus (PNS): asinus tract, or small channel, that may originate from the source of infection and open to the surface of the skin.[10] Material from the cyst drains through the pilonidal sinus. A pilonidal cyst is usually painful, but if it is a draining sinus, the pressure is relieved and the patient might not feel pain.
Hair insertion is the causative agent of pilonidal cysts.[11][12] An analysis of 624 patients' cyst hair found that 74% of the hair was rootless, and resembled spiky, razor-cut hair rather than intact body hair.[11] One proposed cause isingrown hair,[13] although hairs found in pilonidal sinus tracts have more often been found to originate from the head.
Excessive sitting is thought to predispose people to the condition, as sitting increases pressure on thecoccygeal region.
Trauma is not believed to cause a pilonidal cyst; however, such an event may result in inflammation of an existing cyst. There are cases where this has occurred months after a localized injury to the area.
Pilonidal cysts may be caused by a congenitalpilonidal dimple.[14]
Excessive sweating can also contribute to the formation of a pilonidal cyst: moisture can fill a stretched hair follicle, which helps create a low-oxygen environment that promotes the growth ofanaerobic bacteria, often found in pilonidal cysts. The presence of bacteria and low oxygen levels hamper wound healing and exacerbate a developing pilonidal cyst.[15]
A pilonidal cyst can resemble adermoid cyst, a kind ofteratoma (germ cell tumor). In particular, a pilonidal cyst in thegluteal cleft can resemble asacrococcygeal teratoma. Correct diagnosis is important because allteratomas require consultation with anoncologist and complete surgical excision, if possible without any spillage.
If there is an infection, treatment is generally byincision and drainage just off the midline because incisions in the midline have a hard time healing well.[1][2] Following five simple rules has been known to prevent recurring inflammations for some people and avoid surgery: 1. Avoiding chairs and car seats that put pressure on the coccyx; 2. Being of average weight, preferably with lowBMI; 3. Keeping the area clean; 4. Keeping the area dry by wearing exclusively cotton garments; 5. Keeping the area completely hair-free, for example, by regularly using anIPL hair removal device.[16]
The evidence for elective treatment of pilonidal sinus disease is poor.[17] The most commonly performed surgery is for the pilonidal sinus complex to be surgicallyexcised with the wound often left open to heal. Post-surgical wound packing may be necessary, and packing typically must be replaced daily for four to eight weeks. In some cases, two years may be required for completegranulation to occur. Sometimes the cyst is resolved via surgicalmarsupialization.[18]
A 2018 literature review of 740 records of surgeries that included recurrence rates found that primary midline closure surgeries resulted in a 67.9% recurrence rate within 20 years, and recommended that they should be discontinued due to the high recurrence rate.[19] Incision and drainage had a recurrence rate of 25.9% within 2 years, up to 40.2% in 5 years. Phenol treatment has a recurrence rate of 14.1% at 2 years and 40.4% at 5 years.[19] A 2024 study involving 667 people found that, compared with tissue-removing surgery, minor procedures (such as draining and pit-picking) were associated with less pain, fewer complications and a faster recovery. However, minor surgeries were less likely to resolve the condition.[20][21]
Surgeons can also excise the sinus and repair it with a reconstructive flap technique, such as a "cleft lift" procedure or Z-plasty, usually done undergeneral anesthetic. This approach is especially useful for complicated or recurring pilonidal disease, leaves little scar tissue, and flattens the region between the buttocks, reducing the risk of recurrence.[15] This approach typically results in a more rapid recovery than traditional surgery; however, there are fewer surgeons trained in the cleft lift procedure, and it consequently may not be as accessible to patients, depending on their location. Meta-analysis shows recurrence rates were lower in open healing than with primary closure (RR 0.60, 95% CI 0.42 to 0.87), at the expense of healing time.[22] Pilonidal cysts can recur, and do so more frequently if the surgical wound is sutured in the midline, as opposed to away from the midline, which obliterates the natal cleft and removes the focus of shearing stress. An incision lateral to the intergluteal cleft is therefore preferred, especially given the poor healing of midline incisions in this region. Minimally invasive techniques with no wound and rapid return to full activities have been reported but await double-blind randomized trials.[23]
Another technique is to treat the pilonidal sinus withfibrin glue. This technique is of unclear benefit as of 2017 due to insufficient research.[24] The evidence for any treatment is of low quality, and care must be taken not to overinterpret any study in this field.[17]
Since the 2010s, several minimally invasive techniques have been developed to minimize the impact of surgery on patients and achieve less pain and shorter recovery times.[25]
In some cases, the wounds are left open after surgery to heal naturally instead of being closed with stitches. There are a lot of different dressings and topical agents (creams or lotions) that are available to help these open wounds heal. A 2022 systematic review brought together evidence from 11 studies that compared dressings and topical agents for treating open wounds after surgical treatment for pilonidal sinus of the buttocks.[26] The authors concluded that:platelet rich plasma may help wounds to heal quicker compared to sterile gauze; Lietofix skin repair cream may help wounds to heal by 30 days compared toiodine (which helps to reduce bacteria in the wound); but it is not clear whetherhydrogel dressings (designed to keep the wound moist) reduce the time it takes wounds to heal compared with cleaning the wound with iodine.[26]
Endoscopic pilonidal treatment, which uses a small camera to guide the surgeon in removing hair, is a newer method of treatment that has minimal pain and quick healing compared to surgery. A literature review of 497 patients found that the average endoscopic operation time was 34.7 minutes, and the average healing time was 32.9 days. Failure occurred in 8% of patients, who had persistent disease or recurrence.[27]
Pilonidal means 'nest of hair' and is derived from the Latin words for 'hair' (pilus) and 'nest' (nidus).[5] The condition was first described byHerbert Mayo in 1833.[28]R. M. Hodges was the first to use the phrasepilonidal cyst to describe the condition in 1880.[29][30]
The condition was widespread in theUnited States Army duringWorld War II. The condition was termed "Jeep seat" or "Jeep riders' disease", because a large portion of people who were being hospitalized for it rode in Jeeps, and prolonged bumpy rides in the vehicles were believed to have caused the condition due to irritation and pressure on the coccyx.
