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| Names | |
|---|---|
| Other names Choline phosphate | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChemSpider |
|
| MeSH | Phosphocholine |
| UNII | |
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| |
| Properties | |
| C5H15NO4P | |
| Molar mass | 184.151 g/mol |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Phosphocholine is an intermediate in the synthesis ofphosphatidylcholine in tissues. Phosphocholine is made in a reaction, catalyzed bycholine kinase, that convertsATP andcholine into phosphocholine andADP. Phosphocholine is a molecule found, for example, inlecithin.
Innematodes and humanplacentas, phosphocholine is selectively attached to other proteins as aposttranslational modification to suppress an immune response by their hosts.[1][2]
It is also one of the binding targets ofC-reactive protein (CRP).[3] Thus, when a cell is damaged, CRP binds to phosphocholine, beginning the recognition and phagocytotic immunologic response.
Phosphocholine is a natural constituent of hens' eggs (and many other eggs) often used in biomimetic membrane studies.[4][5]
