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Metocurine

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Chemical compound
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Pharmaceutical compound
Metocurine
Identifiers
  • (1β)-6,6',7',12'-tetramethoxy-2,2,2',2'-tetramethyltubocuraran-2,2'-diium
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC40H48N2O6
Molar mass652.832 g·mol−1
3D model (JSmol)
  • C[N+]1(CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C6[C@@H](CC7=CC(=C(C=C7)OC)O3)[N+](CCC6=CC(=C5OC)OC)(C)C)OC)C

Metocurine is amuscle relaxant throughneuromuscular blockade.[1]It is excreted entirely through thekidneys and therefore should not be used in patients withkidney failure.

References

[edit]
  1. ^Fogdall RP (February 1978)."Anesthesiology-epitomes of progress: metocurine-a ;new' muscle relaxant".The Western Journal of Medicine.128 (2):148–9.PMC 1238025.PMID 18748141.
Peripherally acting
(primarilyantinicotinic,
NMJ block)
Non-depolarizing
Curarealkaloids
4° ammonium agents
Depolarizing
ACh release inhibitors
Centrally acting
Carbamic acid esters
Benzodiazepines
Nonbenzodiazepines
Thienodiazepines
Quinazolines
Anticholinergics
(Antimuscarinics)
Other
Directly acting
nAChRsTooltip Nicotinic acetylcholine receptors
Agonists
(andPAMsTooltip positive allosteric modulators)
Antagonists
(andNAMsTooltip negative allosteric modulators)
Precursors
(andprodrugs)


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