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Mannosulfan

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Mannosulfan
Clinical data
Other names[(2R,3S,4S,5R)-3,4-dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl] methanesulfonate
ATC code
Identifiers
  • 1,2,5,6-Tetrakis-O-(methylsulfonyl)-D-mannitol
CAS Number
PubChemCID
ChemSpider
UNII
Chemical and physical data
FormulaC10H22O14S4
Molar mass494.51 g·mol−1
3D model (JSmol)
  • CS(=O)(=O)OC[C@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)C)OS(=O)(=O)C)O)O)OS(=O)(=O)C
  • InChI=1S/C10H22O14S4/c1-25(13,14)21-5-7(23-27(3,17)18)9(11)10(12)8(24-28(4,19)20)6-22-26(2,15)16/h7-12H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1
  • Key:UUVIQYKKKBJYJT-ZYUZMQFOSA-N
  (verify)

Mannosulfan (INN) is analkylating agent with the potential for the treatment ofcancer. It is not approved by the United States FDA for cancer treatment. Research suggests it is less toxic than the alkyl sulfonateBusulfan.[1]

References

[edit]
  1. ^Jeswani G, Paul SD (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents".Nano- and Microscale Drug Delivery Systems. pp. 281–98.doi:10.1016/B978-0-323-52727-9.00015-7.ISBN 978-0-323-52727-9.

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