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Johns Hopkins Center for Health Security

From Wikipedia, the free encyclopedia
Nonprofit biosecurity think tank

Johns Hopkins Center for Health Security
AbbreviationCHS
Formation1998; 28 years ago (1998)[1]
FounderD. A. Henderson[1]
TypeThink tank
Location
Director
Tom Inglesby, MD[2]
Deputy Director
Anita Cicero, JD[3]
Key people
Tara O'Toole
Caitlin Rivers
Tara Kirk
Crystal Watson
Alexandra Phelan
Jassi Pannu
AffiliationsJohns Hopkins Bloomberg School of Public Health
Websitewww.centerforhealthsecurity.org
Formerly called
  • Johns Hopkins Center for Civilian Biodefense Strategies (1998–2003)
  • Center for Biosecurity of UPMC (2003–2013)
  • UPMC Center for Health Security (2013–2017)

TheJohns Hopkins Center for Health Security (abbreviatedCHS) is an independent,nonprofit organization ofJohns Hopkins University and theJohns Hopkins Bloomberg School of Public Health. The Center works to prevent and prepare for epidemics, pandemics and other health disasters. The Center is also concerned with biological weapons prevention and the biosecurity implications of emerging technologies, including artificial intelligence[4] and synthetic biology.

The Center is designated an official Collaborating Centre of theWorld Health Organization and thePan American Health Organization;[5] it provides policy recommendations to governments worldwide including theUnited States Government, theEuropean Union, and the United NationsBiological Weapons Convention.[6]

History

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Founding

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The Center for Health Security was founded in 1998 byD. A. Henderson, the physician who led the successful WHOsmallpox eradication campaign. It was originally named the Johns Hopkins Center for Civilian Biodefense Strategies (CCBS).[7] At that time, the center was the first and only academic center focused on biosecurity policy and practice.[citation needed] Henderson became aware of the Soviet Union's offensive biological weapons program in 1989, which was in direct defiance of the 1972Biological Weapons Convention multilateral disarmament treaty.[8] Routine vaccination against smallpox ended globally in 1980, meaning the use of smallpox as a biological weapon would have catastrophic consequences.

In 1998, the Center was established with a founding team of Dr.Tara O'Toole, Dr.Tom Inglesby, and Dr. Monica Schoch-Spana, with the goal of rigorous research and advocacy to counter bioterrorism and emerging infectious diseases such as pandemic influenza, HIV, and monkeypox. One of their first proposals to theUnited States Government was to procure 40 million doses of stockpiled smallpox vaccine, which was supported by PresidentBill Clinton.[8]

Operation Dark Winter

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In June 2001, the Center hosted a tabletop exercise namedDark Winter in collaboration with theCenter for Strategic and International Studies (CSIS), the Homeland Security Institute (ANSER), and the Oklahoma Memorial Institute for the Prevention of Terrorism.[8]Dark Winter drew an analogy with the destructive power of a nuclear explosion, but instead focused on the catastrophic consequences of an deliberate, weaponized smallpox epidemic.Dark Winter was the first biological weapons tabletop exercise of its kind; media coverage was extensive and six subsequent congressional hearings were held.[8]

Smallpox vaccine stockpiling

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TheSeptember 11 attacks by terrorists on the United States prompted further fear of a biological weapons attack. Subsequent attacks via letters laced withanthrax spores. In preparation for possible follow-on attacks, the Center uncovered that much of the smallpox vaccine stockpile in the US had expired, ultimately prompting then HHS SecretaryTommy Thompson to commit to stockpiling a dose of smallpox vaccine for every person in America. For this purpose, $3 billion was appropriated by Congress.[8] Secretary Thompson requested Henderson assume responsibility for the Office of Public Health Preparedness (later the Office of the Assistant Secretary for Preparedness and Response); O'Toole and Inglesby assumed leadership of the Center and renamed it the Center for Biosecurity. In 2003 it came under the aegis of the University of Pittsburgh.[9]

Atlantic storm

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On January 14, 2005, the Center organized a table-top exercise for senior political leaders from Europe, Canada, and the United States. It was supported by theAlfred P. Sloan Foundation, and theNuclear Threat Initiative. The former Secretary of State Madeleine Albright and former Director General of the WHO and Prime Minister of Norway Dr. Gro Brundtland, were among those that participated.[8]

Johns Hopkins School of Public Health

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In January 2017, the Center returned to theJohns Hopkins Bloomberg School of Public Health under its current name, the Johns Hopkins Center for Health Security.[10]

Funding

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The Center was established in 1998 with 1 year of funding from theUnited States Department of Health and Human Services.[8] In 2000, the Center began receiving funding from theAlfred P. Sloan Foundation,[8] as well as grants from the US federal government.[11]

In January 2017,Coefficient Giving (formerly the Open Philanthropy Project) awarded a $16 million grant over three years to the Center for Health Security;[12][13] this was renewed for $20 million in 2019 and $10 million in 2023.[14]

In 2023 the Center was awarded $23.5 million from the USCenters for Disease Control and Prevention for epidemic preparedness.[15]

Publications

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The Center for Health Security publishes the newsletter:

  • Health Security Decoded, a monthly roundup of top news and developments in health security.

It previously published theClinicians' Biosecurity News (formerly theClinicians' Biosecurity Network Report),[16] andHealth Security Headlines (previously calledBiosecurity Briefing,[17][18][19]Health Security Headlines,[20][21] andPreparedness Pulsepoints.[22]

It maintains and edits the peer-reviewed journalHealth Security[23] which was launched in 2003 and calledBiosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science until 2015.[24]

CHS published theblogThe Bifurcated Needle until 2020.[25]

The center has published in journals includingScience,Nature,JAMA andThe Lancet. A full list of publications is available on the CHS website. As of February 2017[update], the list shows more than 400 publications.[26]

Additional publications:

Major conferences and tabletop exercises

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Operation Dark Winter

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Main article:Operation Dark Winter

From June 22–23, 2001, CHS co-hostedOperation Dark Winter, a senior-level bioterrorism attack simulation involving a covert and widespread smallpox attack on the United States.

Atlantic Storm

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On January 14, 2005, CHS helped to hostAtlantic Storm, a table-topsmallpoxbioterrorism simulation.

Clade X

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On May 15, 2018, the Center hosted Clade X,[27] a day-long pandemic tabletop exercise that simulated a series of National Security Council–convened meetings of 10 US government leaders, played by individuals prominent in the fields of national security or epidemic response.

Drawing from actual events, Clade X identified important policy issues and preparedness challenges that could be solved with sufficient political will and attention. These issues were designed in a narrative to engage and educate the participants and the audience.

Clade X was livestreamed on Facebook and extensive materials from the exercise are available online.[28][29]

Event 201

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On October 18, 2019, the CHS partnered with theWorld Economic Forum and theBill and Melinda Gates Foundation to host the tabletop exercise Event 201 inNew York City.[30][31] According to the CHS, "the exercise illustrated areas where public/private partnerships will be necessary during the response to a severepandemic in order to diminish large-scale economic and societal consequences".[30]

Event 201 simulated the effects of a fictionalcoronavirus passing to humans via infectedpig farms inBrazil with "no possibility of avaccine being available in the first year".[32] The simulation ended after 18 months and projected 65 million deaths from the coronavirus.[32]

Southeast Asia Biosecurity Dialogue

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A series ofTrack II multilateral dialogues cohosted by the Center in the Southeast Asia region ultimately helped to establish theAsia Centre for Health Security.[33]

Artificial intelligence

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Since 2023, the Center has worked extensively on the convergence of artificial intelligence and biotechnology, establishing the shorthand AIxBio within this field.[34]

On November 29, 2023 the Center hosted a convening to discuss pandemic-level biosecurity threats that may arise from artificial intelligence, attended by representatives from theUnited States National Security Council,United States Department of Energy, White House Office of Pandemic Preparedness and Response Policy, United KingdomCabinet Office,OpenAI,Anthropic,Microsoft,Meta,Google DeepMind,Amazon,RAND, and others.[35]

The Center has provided policy recommendations to governments andAI Safety Institutes globally regarding several issues at the intersection of artificial intelligence and biosecurity, including biological data governance, open source models, export controls, risk assessment, model evaluations, and safeguards.[36]

Other

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  • Improving Epidemic Response: Building Bridges Between the US and China. May 2012.
  • Considerations for the Reauthorization of the Pandemic and All-Hazards Preparedness Act (PAHPA). March 2012.
  • U.S. Preparedness for a Nuclear Detonation. October 2011.
  • Charting the Future of Biosecurity: Ten Years After the Anthrax Attacks. October 2011.
  • Advancing US Resilience to a Nuclear Catastrophe. May 2011.
  • Preserving National Security: The Growing Role of the Life Sciences. March 2011.
  • Improving Global Health, Strengthening Global Security. November 2010.
  • The State of BIOPreparedness: Lessons from Leaders, Proposals for Progress. September 2010.
  • Preparing to Save Lives and Recover After a Nuclear Detonation: Implications for US Policy. April 2010.
  • The 2009 H1N1 Experience: Policy Implications for Future Infectious Disease Emergencies. March 2010.
  • Resilient American Communities: Progress In Practice and Policy. December 10, 2009.
  • Prevention of Biothreats: A Look Ahead. October 6, 2009.
  • Disease, Disaster, and Democracy: The Public's Stake in Health Emergency Planning. May 2006.
  • Bulls, Bears, and Birds: Preparing the Financial Industry for a Pandemic. September 2005.
  • Conference on Biosafety and Biorisks. May 2005.
  • The Public as an Asset, Not a Problem: A Summit on Leadership During Bioterrorism. February 2003.
  • 2nd National Symposium on Medical and Public Health Response to Bioterrorism. November 2000.
  • National Symposium on Medical and Public Health Response to Bioterrorism. February 1999.

See also

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References

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  1. ^ab"Our History".Johns Hopkins Center for Health Security. Johns Hopkins School of Public Health. RetrievedNovember 28, 2025.
  2. ^"Tom Inglesby, MD".Johns Hopkins Center for Health Security. Johns Hopkins School of Public Health. RetrievedNovember 28, 2025.
  3. ^"Anita Cicero, JD".Johns Hopkins Center for Health Security. Johns Hopkins University.
  4. ^"AIxBio".Johns Hopkins Center for Health Security. Johns Hopkins University. RetrievedNovember 28, 2025.
  5. ^JHU Center for Health Security (January 22, 2024)."WHO renames Johns Hopkins Center for Health Security as Collaborating Centre for Global Health Security". RetrievedNovember 28, 2025.
  6. ^"Policy & Legislative Priorities".Johns Hopkins Center for Health Security. Johns Hopkins University. RetrievedNovember 28, 2025.
  7. ^"Our People D. A. Henderson, MD, MPH".Johns Hopkins Center for Health Security. Johns Hopkins University. RetrievedNovember 28, 2025.He was Dean Emeritus and Professor at the Johns Hopkins School of Public Health and a Founding Director (1998) of the Johns Hopkins Center for Civilian Biodefense Strategies.
  8. ^abcdefghHenderson, Donald A. (2009). "Chapter 10: Smallpox as a Biological Weapon".Smallpox: the death of a disease: the inside story of eradicating a worldwide killer. Amherst, N.Y: Prometheus Books.ISBN 1591027225.
  9. ^Roos, Robert (September 23, 2003)."Johns Hopkins biodefense experts head in new direction". CIDRAP. RetrievedFebruary 8, 2017.the four full-time faculty members and 16 administrative staff members of the CCBS are all leaving Hopkins to join the UPMC.
  10. ^Price Tyson (January 16, 2017)."Center for Health Security Joins Johns Hopkins Bloomberg School". Johns Hopkins Center for Health Security. RetrievedFebruary 8, 2017.the Center for Health Security, which had previously been affiliated with the University of Pittsburgh Medical Center (UPMC), has joined the Johns Hopkins Bloomberg School of Public Health.
  11. ^"Johns Hopkins Biodefense Center to Receive $1 Million Grant".Johns Hopkins Bloomberg School of Public Health. Johns Hopkins University. RetrievedNovember 29, 2025.
  12. ^"Hopkins' Center for Health Security gets $16M grant". Maryland Daily Record. Associated Press. February 8, 2017. RetrievedFebruary 8, 2017.The Johns Hopkins Bloomberg School of Public Health's Center for Health Security has been awarded a three-year, $16 million grant to support work on strengthening health security and public health preparedness.
  13. ^"Center for Health Security gets $16M grant".The Washington Times. February 8, 2017. RetrievedFebruary 8, 2017.
  14. ^"Biosecurity & Pandemic Preparedness". Coefficient Giving. RetrievedNovember 29, 2025.
  15. ^"Johns Hopkins Center for Health Security Awarded $23.5 Million CDC Grant to Launch New Epidemic Preparedness Project".Johns Hopkins Bloomberg School of Public Health. Johns Hopkins University. RetrievedNovember 29, 2025.
  16. ^"About Clinicians' Biosecurity News | UPMC Center for Health Security".www.upmc-cbn.org.
  17. ^Center for Biosecurity of UPMC (September 21, 2007)."Biosecurity Briefing". Archived from the original on September 27, 2007. RetrievedFebruary 10, 2017.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  18. ^Center for Biosecurity of UPMC (April 30, 2009)."Biosecurity News in Brief -- Center for Biosecurity of UPMC". Archived from the original on May 1, 2009. RetrievedFebruary 10, 2017.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  19. ^Center for Biosecurity of UPMC (July 15, 2011)."Biosecurity News Today". Archived from the original on July 17, 2011. RetrievedFebruary 10, 2017.Biosecurity News Today{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  20. ^Center for Biosecurity of UPMC (August 13, 2012)."Center for Biosecurity | UPMC | Biosecurity News Today". Archived from the original on February 6, 2013. RetrievedFebruary 10, 2017.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  21. ^Center for Biosecurity of UPMC (July 1, 2013)."Health Security Headlines | Published by UPMC Center for Health Security". Archived from the original on July 11, 2013. RetrievedFebruary 10, 2017.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  22. ^Center for Biosecurity of UPMC (January 31, 2017)."Preparedness Pulsepoints". RetrievedFebruary 9, 2017.
  23. ^Rob Adams (January 18, 2017)."Our Work". RetrievedFebruary 9, 2017.Journal: The Center provides editorial oversight for the peer-reviewed journal, Health Security, which is published 6 times per year.
  24. ^"Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science | Issue List". RetrievedFebruary 9, 2017.
  25. ^"About".The Bifurcated Needle. Johns Hopkins Center for Health Security. RetrievedFebruary 10, 2017.
  26. ^"All Publications". RetrievedFebruary 9, 2017.
  27. ^Cizek, Julia (January 7, 2019)."Clade X, a tabletop exercise hosted by the Center for Health Security".Johns Hopkins Center for Health Security. RetrievedJune 24, 2020.
  28. ^Cizek, Julia (January 7, 2019)."Livestream (Archived) from Clade X, a pandemic tabletop exercise".Johns Hopkins Center for Health Security. RetrievedJune 24, 2020.
  29. ^Center, Johns Hopkins (January 7, 2019)."Resources from Clade X, a day-long pandemic tabletop exercise".Johns Hopkins Center for Health Security. RetrievedJune 24, 2020.
  30. ^abJohns Hopkins Center for Health Security (January 24, 2020)."Event 201, a pandemic exercise to illustrate preparedness efforts".Event 201. RetrievedJune 24, 2020.
  31. ^Kirsten Salyer (15 October 2019),"Live Simulation Exercise to Prepare Public and Private Leaders for Pandemic Response", press release fromWorld Economic Forum: "Event 201 exercise will bring together public and private leaders to inform multistakeholder cooperation for pandemic preparedness and response"
  32. ^ab"US rapper Pitbull wrong to claim Event 201 was 'rehearsal' for coronavirus pandemic".Full Fact. February 18, 2021. RetrievedFebruary 21, 2021.
  33. ^"2024 Southeast Asia Dialogue Meeting Materials | Johns Hopkins Center for Health Security".centerforhealthsecurity.org. RetrievedFebruary 27, 2025.
  34. ^"AIxBio Johns Hopkins Center for Health Security".Johns Hopkins Center for Health Security. Johns Hopkins University. RetrievedNovember 29, 2025.
  35. ^"ADVANCING GOVERNANCE FRAMEWORKS FOR FRONTIER AIXBIO"(PDF).Johns Hopkins Center for Health Security. Johns Hopkins University. RetrievedNovember 29, 2025.
  36. ^"AIxBio Johns Hopkins Center for Health Security".Johns Hopkins Center for Health Security. Johns Hopkins University. RetrievedNovember 29, 2025.

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