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Interleukin-12 receptor

From Wikipedia, the free encyclopedia
Type I cytokine receptor

interleukin 12 receptor, beta 1
Identifiers
SymbolIL12RB1
Alt. symbolsIL12RB, CD212
NCBI gene3594
HGNC5971
OMIM601604
RefSeqNM_005535
UniProtP42701
Other data
LocusChr. 19p13.1
Search for
StructuresSwiss-model
DomainsInterPro
beta 2 subunit, interleukin 12 receptor, beta 2
Identifiers
SymbolIL12RB2
NCBI gene3595
HGNC5972
OMIM601642
RefSeqNM_001559
UniProtQ99665
Other data
LocusChr. 1p31.3-31.2
Search for
StructuresSwiss-model
DomainsInterPro

Interleukin 12 receptor is atype I cytokine receptor, bindinginterleukin 12 and consisting ofbeta 1[1] andbeta 2 subunits.[2]

References

[edit]
  1. ^Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994)."Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130".J. Immunol.153 (1):128–36.doi:10.4049/jimmunol.153.1.128.PMID 7911493.S2CID 9211163.
  2. ^Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996)."A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits".Proc. Natl. Acad. Sci. U.S.A.93 (24):14002–14007.Bibcode:1996PNAS...9314002P.doi:10.1073/pnas.93.24.14002.PMC 19484.PMID 8943050.

External links

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Chemokine receptor
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  • See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ)here instead.
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