In vertebrates, the genes encoding the class oftranscription factors calledhomeobox genes are found in clusters named A, B, C, and D on four separate chromosomes.[7] Expression of these proteins is spatially and temporally regulated duringembryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulategene expression,morphogenesis, anddifferentiation.[5]
Peverali FA, D'Esposito M, Acampora D, Bunone G, Negri M, Faiella A, et al. (October 1990). "Expression of HOX homeogenes in human neuroblastoma cell culture lines".Differentiation; Research in Biological Diversity.45 (1):61–69.doi:10.1111/j.1432-0436.1990.tb00458.x.PMID1981366.
Ferguson-Smith AC, Fienberg A, Ruddle FH (August 1989). "Isolation, chromosomal localization, and nucleotide sequence of the human HOX 1.4 homeobox".Genomics.5 (2):250–258.doi:10.1016/0888-7543(89)90054-2.PMID2571574.
Boncinelli E, Acampora D, Pannese M, D'Esposito M, Somma R, Gaudino G, et al. (1990). "Organization of human class I homeobox genes".Genome.31 (2):745–756.doi:10.1139/g89-133.PMID2576652.
Verlinsky Y, Morozov G, Gindilis V, Strom CM, Freidin M, Rechitsky S, et al. (June 1995). "Homeobox gene expression in human oocytes and preembryos".Molecular Reproduction and Development.41 (2):127–132.doi:10.1002/mrd.1080410202.PMID7654365.S2CID43123886.
Apiou F, Flagiello D, Cillo C, Malfoy B, Poupon MF, Dutrillaux B (1996). "Fine mapping of human HOX gene clusters".Cytogenetics and Cell Genetics.73 (1–2):114–115.doi:10.1159/000134320.PMID8646877.
Kuliev A, Kukharenko V, Morozov G, Freidine M, Rechitsky S, Verlinsky O, et al. (February 1996). "Expression of homebox-containing genes in human preimplantation development and in embryos with chromosomal aneuploidies".Journal of Assisted Reproduction and Genetics.13 (2):177–181.doi:10.1007/BF02072541.PMID8688592.S2CID28126784.
Duluc I, Lorentz O, Fritsch C, Leberquier C, Kedinger M, Freund JN (June 1997). "Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells".Journal of Cell Science.110 (11):1317–1324.doi:10.1242/jcs.110.11.1317.PMID9202392.
Kosaki K, Kosaki R, Suzuki T, Yoshihashi H, Takahashi T, Sasaki K, et al. (February 2002). "Complete mutation analysis panel of the 39 human HOX genes".Teratology.65 (2):50–62.doi:10.1002/tera.10009.PMID11857506.
Larramendy ML, Niini T, Elonen E, Nagy B, Ollila J, Vihinen M, et al. (June 2002). "Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis".Haematologica.87 (6):569–577.PMID12031912.
Méchine-Neuville A, Lefebvre O, Bellocq JP, Kedinger M, Simon-Assmann P (December 2002). "[Increased expression of HOXA9 gene in Hirschsprung disease]".Gastroenterologie Clinique et Biologique.26 (12):1110–1117.PMID12520199.
