
Gross pathology, also known as grossing, refers tomacroscopic manifestations ofdisease inorgans,tissues, andbody cavities. The term is commonly used byanatomical pathologists to refer to diagnostically useful findings made during thegross examination portion of surgical specimen processing or anautopsy.
In the intricate process of anatomical pathology, the grossing stage plays a pivotal role. It is vital to systematically explain the gross appearance of a pathological state, for example, a malignant tumor, noting the site, size, shape, consistency, presence of a capsule and appearance on cut section whether well circumscribed or diffusely infiltrating, homogeneous or variegated, cystic, necrotic, hemorrhagic areas, as well as papillary projections.
Therefore, upon receipt of a specimen, pathologists meticulously document its characteristics.[1] They note the specimen's dimensions, hue, texture, and any distinctive features that stand out. This careful observation lays the groundwork for the subsequent steps. Following this, the tissue is delicately sectioned and securely placed into cassettes, each identified by a unique barcode.[2] This systematic approach ensures precision andtraceability, hallmarks of the highest standards inpathology.