TheCore binding factor (CBF) is a group ofheterodimerictranscription factors.

Core binding factors are composed of:

• a non-DNA-binding CBFβ chain (CBFB)
• a DNA-binding CBFα chain (RUNX1,RUNX2,RUNX3)

• de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis and immune function".Oncogene.23 (24):4238–48.doi:10.1038/sj.onc.1207763.PMID 15156179.

• AI-10-49, an anti-leukemic drug under development.

• Core+Binding+Factors at the U.S. National Library of MedicineMedical Subject Headings (MeSH)

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