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AMOTL2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
AMOTL2
Identifiers
AliasesAMOTL2, LCCP, angiomotin like 2
External IDsOMIM:614658;MGI:1929286;HomoloGene:9420;GeneCards:AMOTL2;OMA:AMOTL2 - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for AMOTL2
Genomic location for AMOTL2
Band3q22.2Start134,355,347bp[1]
End134,375,479bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for AMOTL2
Genomic location for AMOTL2
Band9|9 F1Start102,593,871bp[2]
End102,610,617bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • amniotic fluid

  • sural nerve

  • lactiferous duct

  • inferior ganglion of vagus nerve

  • right coronary artery

  • renal medulla

  • ventricular zone

  • germinal epithelium

  • synovial joint

  • parietal pleura
Top expressed in
  • calvaria

  • adrenal gland

  • right lung

  • ankle

  • ventricular zone

  • white adipose tissue

  • stroma of bone marrow

  • vestibular membrane of cochlear duct

  • lip

  • right lung lobe
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51421

56332

Ensembl

ENSG00000114019

ENSMUSG00000032531

UniProt

Q9Y2J4

Q8K371

RefSeq (mRNA)

NM_001278683
NM_001278685
NM_016201
NM_001363943

NM_019764

RefSeq (protein)

NP_001265612
NP_001265614
NP_057285
NP_001350872

NP_062738

Location (UCSC)Chr 3: 134.36 – 134.38 MbChr 9: 102.59 – 102.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Angiomotin-like protein 2 is aprotein that in humans is encoded by theAMOTL2gene.[5]

Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.[5]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000114019Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000032531Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: AMOTL2 angiomotin like 2".

External links

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Further reading

[edit]


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