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| Names | |
|---|---|
| IUPAC name 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methylchromen-4-one | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChemSpider | |
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| Properties | |
| C16H12O5 | |
| Molar mass | 284.267 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
6-Methylapigenin is a naturally occurringflavonoid and a derivative ofapigenin. It has activity atGABAA receptors as a positive modulator.
6-Methylapigenin can be found in multiple plants, such asValeriana officinalis,Valeriana jatamansi, andPicea neoveitchii.[1]
6-Methylapigenin binds to theGABAA receptor on thebenzodiazepine binding site. This compound possessesanxiolytic effects. In a mouse model, it is also able to potentiate sleep induced byhesperidin, anotherflavonoid.[2][3] However, since it does not have the chemical structure ofbenzodiazepines, it can therefore be classed as anonbenzodiazepine.
