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2C-T-30

From Wikipedia, the free encyclopedia

Pharmaceutical compound
2C-T-30
Clinical data
Other names2C-T-FB; 2C-T-FBu; 4-(4-Fluorobutylthio)-2,5-dimethoxyphenethylamine
Routes of
administration		Oral[1]
Drug classSerotonin receptor modulator;Serotonin 5-HT2A receptor agonist
ATC code
  • None
Identifiers
  • 2-[4-(4-fluorobutylsulfanyl)-2,5-dimethoxyphenyl]ethanamine
PubChemCID
Chemical and physical data
FormulaC14H22FNO2S
Molar mass287.39 g·mol−1
3D model (JSmol)
  • COC1=CC(=C(C=C1CCN)OC)SCCCCF
  • InChI=1S/C14H22FNO2S/c1-17-12-10-14(19-8-4-3-6-15)13(18-2)9-11(12)5-7-16/h9-10H,3-8,16H2,1-2H3
  • Key:BILSBDMCLLFSAV-UHFFFAOYSA-N

2C-T-30, also known as4-(4-fluorobutylthio)-2,5-dimethoxyphenethylamine or as2C-T-FB, is aserotonin receptor modulator of thephenethylamine and2C families.[1][2][3] It is thederivative of2C-T in which the 4-methylthiogroup has been replaced with a 4-(4-fluorobutylthio) group.[1][2] According toDaniel Trachsel, 2C-T-30 was not clearly active at a dose of 6 mg plus 3 mgorally and itsduration and effects are unknown.[2][4] However, it was said that it might have helped increaseability to concentrate on tasks.[2] The drug is apotentpartial agonist of theserotonin5-HT2A receptor and also interacts with otherserotonin receptors andtargets.[3][1] Thechemical synthesis of 2C-T-30 has been described.[5] 2C-T-30 was first described in thescientific literature by Trachsel in 2003.[5] It is acontrolled substance inCanada under phenethylamine blanket-ban language.[6]

See also

[edit]

References

[edit]
  1. ^abcdTrachsel D, Lehmann D, Enzensperger C (2013).Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag.ISBN 978-3-03788-700-4.OCLC 858805226. Archived fromthe original on 21 August 2025.
  2. ^abcdTrachsel D (2012). "Fluorine in psychedelic phenethylamines".Drug Testing and Analysis.4 (7–8):577–590.doi:10.1002/dta.413.PMID 22374819.Further homologs, 2C-T-19 (41; Ki = 14nM) and 2C-T-30 (42; Ki = 47nM) were tested in radioligand binding assays using [3 H] LSD labelled cloned h5-HT2A receptors, indicating a high affinity of 41 at this binding site. In this case fluorine seemed to decrease affinity slightly by a factor of around three. Virtually nothing is known about their human activities. 2C-T-30 (42) was tested up to 6 + 3 mg which revealed no detectable effects.
  3. ^abLuethi D, Trachsel D, Hoener MC, Liechti ME (May 2018). "Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs)".Neuropharmacology.134 (Pt A):141–148.doi:10.1016/j.neuropharm.2017.07.012.PMID 28720478.
  4. ^Luethi D, Liechti ME (October 2018)."Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics".The International Journal of Neuropsychopharmacology.21 (10):926–931.doi:10.1093/ijnp/pyy047.PMC 6165951.PMID 29850881.
  5. ^abTrachsel D (2003)."Synthese von neuen (Phenylalkyl)aminen zur Untersuchung von Struktur–Aktivitätsbeziehungen. Mitteilung 2: 4-Thio-substituierte [2-(2,5-Dimethoxyphenyl)ethyl]amine (=2,5-Dimethoxybenzolethanamine)".Helvetica Chimica Acta.86 (7):2610–2619.doi:10.1002/hlca.200390210.ISSN 0018-019X. Retrieved17 November 2025.
  6. ^"Controlled Drugs and Substances Act".Department of Justice Canada. Retrieved19 January 2026.

External links

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