| 2010 Serbia Open | |
|---|---|
| Date | 3–9 May |
| Edition | 2nd |
| Category | ATP World Tour 250 |
| Prize money | €373,200 |
| Surface | Clay / outdoor |
| Location | Belgrade, Serbia |
| Venue | Milan Gale Muškatirović |
| Champions | |
| Singles | |
| Doubles | |
The2010Serbia Open (also known asSerbia Open powered byTelekom Srbija for sponsorship reasons) was a men'stennis tournament played on outdoorclay courts. It was the 2nd edition of the event. It was part of theATP World Tour 250 series of the2010 ATP World Tour. It took place at the Milan Gale Muškatirović complex inBelgrade,Serbia, from 3 May through 9 May 2010.
The singles draw featured the tournament's host,ATP ranked No. 2 and defending championNovak Djokovic. Other featured stars were2010 Grand Prix Hassan II championStan Wawrinka,2010 Regions Morgan Keegan Championships championSam Querrey and2010 Heineken Open championJohn Isner. Third-seeded Isner won the singles title.

| Player | Nationality | Ranking* | Seeding |
|---|---|---|---|
| Novak Djokovic | 2 | 1 | |
| John Isner | United States | 22 | 2 |
| Sam Querrey | United States | 23 | 3 |
| Stanislas Wawrinka | 26 | 4 | |
| Ivo Karlović | 30 | 5 | |
| Viktor Troicki | 37 | 6 | |
| Janko Tipsarević | 38 | 7 | |
| Andreas Seppi | 47 | 8 |
The following players receivedwildcards into the main draw:
The following players received entry from the qualifying draw:
Sam Querrey defeated
John Isner, 3–6, 7–6(7–4), 6-4
Santiago González /
Travis Rettenmaier defeated
Tomasz Bednarek /
Mateusz Kowalczyk, 7–6(8–6), 6–1