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2,α-Dimethyltryptamine

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
2,α-Dimethyltryptamine
Clinical data
Other names2,α-DMT; 2-Methyl-α-methyltryptamine; 2-Methyl-AMT; 2-Methyl-αMT; 2-Me-AMT; 2-Me-αMT
Routes of
administration
Oral
ATC code
  • None
Identifiers
  • 1-(2-methyl-1H-indol-3-yl)propan-2-amine
CAS Number
ChemSpider
UNII
Chemical and physical data
FormulaC12H16N2
Molar mass188.274 g·mol−1
3D model (JSmol)
  • Cc1c(c2ccccc2[nH]1)CC(C)N
  • InChI=1S/C12H16N2/c1-8(13)7-11-9(2)14-12-6-4-3-5-10(11)12/h3-6,8,14H,7,13H2,1-2H3 checkY
  • Key:AXZQFXRPULJFQK-UHFFFAOYSA-N checkY
  (verify)

2,α-Dimethyltryptamine (2,α-DMT), also known as2-methyl-α-methyltryptamine (2-Me-αMT or2-Me-AMT), is atryptamine and a lesser-knownpsychedelic drug.[1] It is the 2,α-dimethylanalogue ofDMT and the 2-methylderivative ofα-methyltryptamine (αMT or AMT).[1]

Use and effects

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In his bookTiHKAL (Tryptamines I Have Known and Loved),Alexander Shulgin lists 2,α-DMT's dose as 300 to 500 mgorally and itsduration as 7 to 10 hours.[1] The effects of 2,α-DMT have been reported to includefeeling intoxicated ordrunk-like, feeling good and peaceful, things feeling softer and richer, brighter lights, flashes on edge ofvisual field,daydreaming withmusic, completely clear thinking, eating food being an adventure, facialtingling, impairedmotor coordination, easysleep, and next-daydehydration.[1]

Chemistry

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Synthesis

[edit]

Thechemical synthesis of 2,α-DMT has been described.[1]

Analogues

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Analogues of 2,α-DMT (2-methyl-AMT) include2-methyltryptamine (2-MT or 2-Me-T),2,N,N-TMT (2-methyl-DMT),2-methyl-DET, and5-MeO-2-TMT (2-methyl-5-MeO-DMT), among others.[1]

History

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Thechemical synthesis of 2,α-DMT was first reported in 1965.[2]

See also

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References

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  1. ^abcdefShulgin A,Shulgin A (September 1997).TiHKAL: The Continuation.Berkeley, California:Transform Press. p. 422.ISBN 0-9630096-9-9.OCLC 38503252.
  2. ^Heath-Brown B, Philpott PG (1965). "Studies in the Indole Series. Part I. Indolylalkylamines".Journal of the Chemical Society (Dec):7165–7178.doi:10.1039/jr9650007165.

External links

[edit]
Tryptamines
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