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MPEP (drug)

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(Redirected from1-(α-Methylphenethyl)pyrrolidine)

Pharmaceutical compound
MPEP (drug)
Clinical data
Other names1-(α-Methylphenethyl)pyrrolidine; α-Methylphenethylpyrrolidine; α-Methyl-PEP; 1-(1-Methyl-2-phenylethyl)pyrrolidine
Drug classStimulant
ATC code
  • None
Identifiers
  • 1-(1-phenylpropan-2-yl)pyrrolidine
PubChemCID
ChemSpider
Chemical and physical data
FormulaC13H19N
Molar mass189.302 g·mol−1
3D model (JSmol)
  • CC(CC1=CC=CC=C1)N2CCCC2
  • InChI=1S/C13H19N/c1-12(14-9-5-6-10-14)11-13-7-3-2-4-8-13/h2-4,7-8,12H,5-6,9-11H2,1H3
  • Key:AWNZMWZMSDWFCV-UHFFFAOYSA-N

MPEP, also known as1-(α-methylphenethyl)pyrrolidine, is astimulantdrug of thephenethylamine,amphetamine, andphenylethylpyrrolidine families.[1][2] It is the α-methylderivative ofphenylethylpyrrolidine (PEP).[1][2] Notablederivatives of MPEP includeprolintane (the α-propylhomologue),α-PPP (the β-keto orcathinone derivative),α-PVP (the β-keto and α-propyl homologue),pyrovalerone (4-methyl-α-PVP), andMDPV (3,4-methylenedioxy-α-PVP), among others.[1][3] These compounds are known to act asnorepinephrine–dopamine reuptake inhibitors (NDRIs) to produce theirstimulant effects.[1][3] MPEP was first described in thescientific literature by R. V. Heinzelman and B. D. Aspergren by 1953.[1][2]

See also

[edit]

References

[edit]
  1. ^abcdeGlennon RA (2014). "Bath salts, mephedrone, and methylenedioxypyrovalerone as emerging illicit drugs that will need targeted therapeutic intervention".Emerging Targets & Therapeutics in the Treatment of Psychostimulant Abuse. Advances in Pharmacology. Vol. 69. pp. 581–620.doi:10.1016/B978-0-12-420118-7.00015-9.ISBN 978-0-12-420118-7.PMC 4471862.PMID 24484988.
  2. ^abcHeinzelman RV, Aspergren BD (1953)."Compounds Containing the Pyrrolidine Ring. Analogs of Sympathomimetic Amines".Journal of the American Chemical Society.75 (14):3409–3413.Bibcode:1953JAChS..75.3409H.doi:10.1021/ja01110a033.ISSN 0002-7863. Retrieved11 November 2025.
  3. ^abLuethi D, Liechti ME (April 2020)."Designer drugs: mechanism of action and adverse effects".Archives of Toxicology.94 (4):1085–1133.Bibcode:2020ArTox..94.1085L.doi:10.1007/s00204-020-02693-7.PMC 7225206.PMID 32249347.

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