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About:Tirabrutinib

An Entity of Type:chemical substance,from Named Graph:http://dbpedia.org,within Data Space:dbpedia.org

Tirabrutinib (brand name Velexbru) is a drug used for the treatment of autoimmune disorders and hematological malignancies. Tirabrutinib was approved in March 2020 in Japan for the treatment of recurrent or refractory primary central nervous system lymphoma. In addition, tirabrutinib is in clinical development by Ono Pharmaceutical and Gilead Sciences in the United States, Europe, and Japan for autoimmune disorders, chronic lymphocytic leukemia, B cell lymphoma, Sjogren's syndrome, pemphigus, and rheumatoid arthritis. Tirabrutinib is an irreversible inhibitor of Bruton's tyrosine kinase.

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  • Tirabrutinib (brand name Velexbru) is a drug used for the treatment of autoimmune disorders and hematological malignancies. Tirabrutinib was approved in March 2020 in Japan for the treatment of recurrent or refractory primary central nervous system lymphoma. In addition, tirabrutinib is in clinical development by Ono Pharmaceutical and Gilead Sciences in the United States, Europe, and Japan for autoimmune disorders, chronic lymphocytic leukemia, B cell lymphoma, Sjogren's syndrome, pemphigus, and rheumatoid arthritis. Tirabrutinib is an irreversible inhibitor of Bruton's tyrosine kinase. (en)
dbo:alternativeName
  • Velexbru (en)
dbo:casNumber
  • 1351636-18-4
dbo:chEMBL
  • 4071161
dbo:drugbank
  • DB15227
dbo:fdaUniiCode
  • LXG44NDL2T
dbo:pubchem
  • 54755438
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  • 67965403 (xsd:integer)
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  • 4182 (xsd:nonNegativeInteger)
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  • 1033073415 (xsd:integer)
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  • 25 (xsd:integer)
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  • 1351636 (xsd:integer)
dbp:chembl
  • 4071161 (xsd:integer)
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  • 58171734 (xsd:integer)
dbp:drugbank
  • DB15227 (en)
dbp:h
  • 22 (xsd:integer)
dbp:iupacName
  • 6 (xsd:integer)
dbp:legalStatus
  • Rx-only (en)
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  • 6 (xsd:integer)
dbp:o
  • 3 (xsd:integer)
dbp:pubchem
  • 54755438 (xsd:integer)
dbp:synonyms
  • GS-4059; ONO-4059 (en)
dbp:tradename
  • Velexbru (en)
dbp:unii
  • LXG44NDL2T (en)
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rdfs:comment
  • Tirabrutinib (brand name Velexbru) is a drug used for the treatment of autoimmune disorders and hematological malignancies. Tirabrutinib was approved in March 2020 in Japan for the treatment of recurrent or refractory primary central nervous system lymphoma. In addition, tirabrutinib is in clinical development by Ono Pharmaceutical and Gilead Sciences in the United States, Europe, and Japan for autoimmune disorders, chronic lymphocytic leukemia, B cell lymphoma, Sjogren's syndrome, pemphigus, and rheumatoid arthritis. Tirabrutinib is an irreversible inhibitor of Bruton's tyrosine kinase. (en)
rdfs:label
  • Tirabrutinib (en)
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