| dbo:abstract | - Plasmacytoma is a plasma cell dyscrasia in which a plasma cell tumour grows within soft tissue or within the axial skeleton. The International Myeloma Working Group lists three types: solitary plasmacytoma of bone (SPB); extramedullary plasmacytoma (EP), and multiple plasmacytomas that are either primary or recurrent. The most common of these is SPB, accounting for 3–5% of all plasma cell malignancies. SPBs occur as lytic lesions within the axial skeleton and extramedullary plasmacytomas most often occur in the upper respiratory tract (85%), but can occur in any soft tissue. Approximately half of all cases produce paraproteinemia. SPBs and extramedullary plasmacytomas are mostly treated with radiotherapy, but surgery is used in some cases of extramedullary plasmacytoma. The skeletal forms frequently progress to multiple myeloma over the course of 2–4 years. Due to their cellular similarity, plasmacytomas have to be differentiated from multiple myeloma. For SPB and extramedullary plasmacytoma the distinction is the presence of only one lesion (either in bone or soft tissue), normal bone marrow (<5% plasma cells), normal skeletal survey, absent or low paraprotein and no end organ damage. (en)
- Un plasmocytome ou plasmacytome, est une tumeur maligne développée à partir de plasmocytes, cellules représentant le stade final de différenciation des lymphocytes B, productrices d'anticorps et d'immunoglobulines. Un plasmocytome peut être, rarement, localisé à un os ou un autre organe, on parle alors de : * Plasmocytome osseux solitaire * Tumeur plasmocytaire extra-osseuse Le plus souvent il s'agit d'un cancer généralisé : un myélome multiple. (fr)
- Il plasmocitoma è un tumore maligno delle plasmacellule. Molti casi di plasmocitoma producono una . Purtroppo la terminologia può indurre in ambiguità, a causa delle successive modificazioni della denominazione durante gli anni. (it)
- Een plasmocytoom is een kwaadaardige tumor bestaande uit een woekering van plasmacellen. Deze vorm van kanker komt meestal voor als onderdeel van de ziekte van Kahler en soms als een plasmacytoïde uitrijping van een lymfoom. (nl)
- Plasmocitoma ou plasmacitoma é uma neoplasia de linfocitos B periféricos (plasmócitos). Se apresentam como lesão solitaria em osso e partes blandas, sendo que as lesões osseas afetam mejoritariamente ao esqueleto axial (vertebras, costelas, craneo, pelvis, clavícula, escapula e fémur). As lesoes começam na cavidade medular, erosionam ao osso esponjoso e destroem progressivamente a corteza óssea, causando fraturas patológicas (mais frequentes em vertebras)As lesões extra osseas se localizam em senos nasais, faringe e pulmoes.O Plasmocitoma Solitario evolue quase inevitavelmente à Mieloma Multiplo, porem podem tardar 10 a 30 anos ou mais. Os Plasmocitomas Solitarios extra osseos que afetam a vias aéreas superiores, se curam mediante ressecção local. (pt)
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| dbp:caption | - Micrograph of a plasmacytoma. H&E stain. (en)
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| dbp:emedicinetopic | |
| dbp:field | - Hematology and oncology (en)
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| rdfs:comment | - Un plasmocytome ou plasmacytome, est une tumeur maligne développée à partir de plasmocytes, cellules représentant le stade final de différenciation des lymphocytes B, productrices d'anticorps et d'immunoglobulines. Un plasmocytome peut être, rarement, localisé à un os ou un autre organe, on parle alors de : * Plasmocytome osseux solitaire * Tumeur plasmocytaire extra-osseuse Le plus souvent il s'agit d'un cancer généralisé : un myélome multiple. (fr)
- Il plasmocitoma è un tumore maligno delle plasmacellule. Molti casi di plasmocitoma producono una . Purtroppo la terminologia può indurre in ambiguità, a causa delle successive modificazioni della denominazione durante gli anni. (it)
- Een plasmocytoom is een kwaadaardige tumor bestaande uit een woekering van plasmacellen. Deze vorm van kanker komt meestal voor als onderdeel van de ziekte van Kahler en soms als een plasmacytoïde uitrijping van een lymfoom. (nl)
- Plasmocitoma ou plasmacitoma é uma neoplasia de linfocitos B periféricos (plasmócitos). Se apresentam como lesão solitaria em osso e partes blandas, sendo que as lesões osseas afetam mejoritariamente ao esqueleto axial (vertebras, costelas, craneo, pelvis, clavícula, escapula e fémur). As lesoes começam na cavidade medular, erosionam ao osso esponjoso e destroem progressivamente a corteza óssea, causando fraturas patológicas (mais frequentes em vertebras)As lesões extra osseas se localizam em senos nasais, faringe e pulmoes.O Plasmocitoma Solitario evolue quase inevitavelmente à Mieloma Multiplo, porem podem tardar 10 a 30 anos ou mais. Os Plasmocitomas Solitarios extra osseos que afetam a vias aéreas superiores, se curam mediante ressecção local. (pt)
- Plasmacytoma is a plasma cell dyscrasia in which a plasma cell tumour grows within soft tissue or within the axial skeleton. The International Myeloma Working Group lists three types: solitary plasmacytoma of bone (SPB); extramedullary plasmacytoma (EP), and multiple plasmacytomas that are either primary or recurrent. The most common of these is SPB, accounting for 3–5% of all plasma cell malignancies. SPBs occur as lytic lesions within the axial skeleton and extramedullary plasmacytomas most often occur in the upper respiratory tract (85%), but can occur in any soft tissue. Approximately half of all cases produce paraproteinemia. SPBs and extramedullary plasmacytomas are mostly treated with radiotherapy, but surgery is used in some cases of extramedullary plasmacytoma. The skeletal forms (en)
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| rdfs:label | - Plasmocitoma (it)
- Plasmocytome (fr)
- Plasmacytoma (en)
- Plasmocytoom (nl)
- Plasmocitoma (pt)
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