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The Macondo Prospect (Mississippi Canyon Block 252, abbreviated MC252) is an oil and gas prospect in the United States Exclusive Economic Zone of the Gulf of Mexico, off the coast of Louisiana. The prospect was the site of the Deepwater Horizon drilling rig explosion in April 2010 that led to a major oil spill in the region from the first exploration well, named itself MC252-1 (nicknamed also Macondo-1), which had been designed to investigate the existence of the prospect.