About:LY-367,265

An Entity of Type:chemical substance,from Named Graph:http://dbpedia.org,within Data Space:dbpedia.org

LY-367,265 is a drug developed by Eli Lilly, which acts as both a potent and selective antagonist at the serotonin 5-HT2A receptor, and also a selective serotonin reuptake inhibitor (SSRI). It has antidepressant effects in animal studies, reduces glutamate signalling in the brain and increases the analgesic effects of morphine.

Property	Value
dbo:abstract	LY-367,265 is a drug developed by Eli Lilly, which acts as both a potent and selective antagonist at the serotonin 5-HT2A receptor, and also a selective serotonin reuptake inhibitor (SSRI). It has antidepressant effects in animal studies, reduces glutamate signalling in the brain and increases the analgesic effects of morphine. (en)
dbo:casNumber	210751-39-6
dbo:chEBI	183634
dbo:fdaUniiCode	SS58UXZ8ZU
dbo:pubchem	4605800
dbo:thumbnail	wiki-commons:Special:FilePath/LY-367265_structure.png?width=300
dbo:wikiPageID	40779105 (xsd:integer)
dbo:wikiPageLength	3102 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1054344312 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Eli_Lilly_and_Company dbr:Morphine dbr:Antidepressant dbr:5-HT2A_receptor dbc:5-HT2A_antagonists dbr:Receptor_(biochemistry) dbc:Eli_Lilly_and_Company_brands dbc:Selective_serotonin_reuptake_inhibitors dbr:Selective_serotonin_reuptake_inhibitor dbr:Serotonin dbr:Glutamate dbr:Antagonist_(pharmacology)
dbp:c	24 (xsd:integer)
dbp:casNumber	210751 (xsd:integer)
dbp:chebi	183634 (xsd:integer)
dbp:chemspiderid	3797242 (xsd:integer)
dbp:f	1 (xsd:integer)
dbp:h	25 (xsd:integer)
dbp:iupacName	1 (xsd:integer)
dbp:n	4 (xsd:integer)
dbp:o	2 (xsd:integer)
dbp:pubchem	4605800 (xsd:integer)
dbp:s	1 (xsd:integer)
dbp:smiles	FC1=CC=C2C=C1 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	BJIPVHLRWSDKOS-UHFFFAOYSA-N (en)
dbp:unii	SS58UXZ8ZU (en)
dbp:width	260 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Nervous-system-drug-stub dbt:Reflist dbt:Serotonergics dbt:Drugbankcite dbt:Fdacite
dcterms:subject	dbc:5-HT2A_antagonists dbc:Eli_Lilly_and_Company_brands dbc:Selective_serotonin_reuptake_inhibitors
gold:hypernym	dbr:Drug
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Adversary109773245 yago:CausalAgent100007347 yago:LivingThing100004258 yago:Object100002684 yago:Organism100004475 yago:Person100007846 yago:PhysicalEntity100001930 yago:YagoLegalActor yago:YagoLegalActorGeo dbo:Drug yago:Whole100003553 yago:Wikicat5-HT2AAntagonists
rdfs:comment	LY-367,265 is a drug developed by Eli Lilly, which acts as both a potent and selective antagonist at the serotonin 5-HT2A receptor, and also a selective serotonin reuptake inhibitor (SSRI). It has antidepressant effects in animal studies, reduces glutamate signalling in the brain and increases the analgesic effects of morphine. (en)
rdfs:label	LY-367,265 (en)
owl:sameAs	freebase:LY-367,265 yago-res:LY-367,265 wikidata:LY-367,265 dbpedia-sh:LY-367,265 dbpedia-sr:LY-367,265 https://global.dbpedia.org/id/YFSD
prov:wasDerivedFrom	wikipedia-en:LY-367,265?oldid=1054344312&ns=0
foaf:depiction	wiki-commons:Special:FilePath/LY-367265_structure.png
foaf:isPrimaryTopicOf	wikipedia-en:LY-367,265
isdbo:wikiPageWikiLink of	dbr:SB-649,915 dbr:SN-22 dbr:5-HT2A_receptor
isfoaf:primaryTopic of	wikipedia-en:LY-367,265

Movatterモバイル変換

About:LY-367,265