dbo:abstract | - Fluorometholone acetate, also known as oxylone acetate and sold under the brand names Flarex, Florate, and Omnitrol, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester, as well as a progestogen and progestogen ester. It is the C17α acetate ester of fluorometholone. In addition to its potent corticosteroid activity, fluorometholone acetate is a progestogen. It has been studied in the treatment of breast cancer in women and has been found to be effective, producing remission in about 20% of women with advanced breast cancer at an oral dosage of 50 mg/day. However, it also produces severe Cushing's syndrome-like symptoms like plethora, moon face, glycosuria, marked weight gain, hypertension, and osteoporosis at this dosage due to its glucocorticoid activity. (en)
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dbo:alternativeName | - Flarex, Florate, Omnitrol (en)
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dbp:iupacName | - [-17-acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate (en)
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dbp:smiles | - [H][C@@]12CC[C@][C@@]1C[C@][C@@]1[C@@]2C[C@]C2=CCC=C[C@]12C (en)
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dbp:synonyms | - Oxylone acetate; 1-Dehydro-9α-fluoro-11β,17α-dihydroxy-6α-methylprogesterone 17α-acetate; 17α-Acetoxy-9α-fluoro-11β-hydroxy-6α-methylpregna-1,4-diene-3,20-dione (en)
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dbp:tradename | - Flarex, Florate, Omnitrol (en)
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rdfs:comment | - Fluorometholone acetate, also known as oxylone acetate and sold under the brand names Flarex, Florate, and Omnitrol, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester, as well as a progestogen and progestogen ester. It is the C17α acetate ester of fluorometholone. (en)
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rdfs:label | - Fluorometholone acetate (en)
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