This content was extracted fromWikipedia and is licensed under theCreative Commons Attribution-ShareAlike 3.0 Unported License
ERB-79 is a synthetic estrogen and a selective agonist of the ERβ. It is a racemic mixture, with the active enantiomer being ERB-26. ERB-79 shows more than 484-fold selectivity for transactivation of the ERβ over the ERα. Its EC50 value for the ERβ is 0.448 nM (14.52% of the potency of estradiol) and for the ERα is 79 nM (0.03% of the potency of estradiol). It has no antagonistic activity at either receptor. ERB-79 is active in preclinical models of arthritis. The chemical structure of ERB-79 does not appear to have been disclosed.
| Property | Value |
|---|---|
| dbo:abstract |
|
| dbo:casNumber |
|
| dbo:class | |
| dbo:wikiPageID |
|
| dbo:wikiPageLength |
|
| dbo:wikiPageRevisionID |
|
| dbo:wikiPageWikiLink |
|
| dbp:casNumber |
|
| dbp:class |
|
| dbp:wikiPageUsesTemplate | |
| dcterms:subject | |
| rdf:type | |
| rdfs:comment |
|
| rdfs:label |
|
| owl:sameAs | |
| prov:wasDerivedFrom | |
| foaf:isPrimaryTopicOf | |
| isdbo:wikiPageRedirects of | |
| isdbo:wikiPageWikiLink of | |
| isfoaf:primaryTopic of |