Implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis. Such an interim analysis can either be blinded or unblinded. Code is provided for Normally distributed endpoints with known variance, with a prominent example being the hazard ratio.
| Version: | 1.0.6 |
| Depends: | mvtnorm, R (≥ 3.5.0) |
| Suggests: | knitr,rmarkdown |
| Published: | 2025-02-22 |
| DOI: | 10.32614/CRAN.package.bpp |
| Author: | Kaspar Rufibach [aut, cre], Paul Jordan [aut], Markus Abt [aut] |
| Maintainer: | Kaspar Rufibach <kaspar.rufibach at gmail.com> |
| License: | GPL-2 |GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | bpp results |
| Reference manual: | bpp.html ,bpp.pdf |
| Vignettes: | Sequentially updating the likelihood of success of a Phase 3 pivotal time-to-event trial based on interim analyses or external information (source,R code) |
| Package source: | bpp_1.0.6.tar.gz |
| Windows binaries: | r-devel:bpp_1.0.6.zip, r-release:bpp_1.0.6.zip, r-oldrel:bpp_1.0.6.zip |
| macOS binaries: | r-release (arm64):bpp_1.0.6.tgz, r-oldrel (arm64):bpp_1.0.6.tgz, r-release (x86_64):bpp_1.0.6.tgz, r-oldrel (x86_64):bpp_1.0.6.tgz |
| Old sources: | bpp archive |
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