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twosigma: DE Analysis for Single-Cell RNA-Sequencing Data

Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) <doi:10.1002/gepi.22361> and Van Buren et al. (2021) <doi:10.1101/2021.01.24.427979>.

Version:1.0.2
Imports:multcomp (≥ 1.4-13),glmmTMB, methods,pscl (≥ 1.5.5),pbapply (≥ 1.4.0), parallel (≥ 3.6.3),doParallel (≥ 1.0.15)
Suggests:testthat
Published:2021-12-13
DOI:10.32614/CRAN.package.twosigma
Author:Eric Van Buren [aut, cre], Yun Li [aut], Di Wu [aut], Ming Hu [aut]
Maintainer:Eric Van Buren <edvanburen at gmail.com>
BugReports:https://github.com/edvanburen/twosigma/issues
License:AGPL-3
URL:https://github.com/edvanburen/twosigma
NeedsCompilation:no
Materials:README,NEWS
CRAN checks:twosigma results

Documentation:

Reference manual:twosigma.html ,twosigma.pdf

Downloads:

Package source: twosigma_1.0.2.tar.gz
Windows binaries: r-devel:twosigma_1.0.2.zip, r-release:twosigma_1.0.2.zip, r-oldrel:twosigma_1.0.2.zip
macOS binaries: r-release (arm64):twosigma_1.0.2.tgz, r-oldrel (arm64):twosigma_1.0.2.tgz, r-release (x86_64):twosigma_1.0.2.tgz, r-oldrel (x86_64):twosigma_1.0.2.tgz

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=twosigmato link to this page.


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