DTSEA: Drug Target Set Enrichment Analysis
It is a novel tool used to identify the candidate drugs against a particular disease based on the drug target set enrichment analysis. It assumes the most effective drugs are those with a closer affinity in the protein-protein interaction network to the specified disease. (See Gómez-Carballa et al. (2022) <doi:10.1016/j.envres.2022.112890> and Feng et al. (2022) <doi:10.7150/ijms.67815> for disease expression profiles; see Wishart et al. (2018) <doi:10.1093/nar/gkx1037> and Gaulton et al. (2017) <doi:10.1093/nar/gkw1074> for drug target information; see Kanehisa et al. (2021) <doi:10.1093/nar/gkaa970> for the details of KEGG database.)
| Version: | 0.0.3 |
| Depends: | R (≥ 4.0.0) |
| Imports: | dplyr,fgsea,igraph,magrittr,tibble,tidyr,BiocParallel,stringr |
| Suggests: | knitr,rmarkdown |
| Published: | 2022-11-06 |
| DOI: | 10.32614/CRAN.package.DTSEA |
| Author: | Junwei Han [aut, cre, cph], Yinchun Su [aut] |
| Maintainer: | Junwei Han <hanjunwei1981 at 163.com> |
| License: | GPL-2 |GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| Materials: | README,NEWS |
| CRAN checks: | DTSEA results |
Documentation:
Downloads:
Linking:
Please use the canonical formhttps://CRAN.R-project.org/package=DTSEAto link to this page.