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adjclust: Adjacency-Constrained Clustering of a Block-Diagonal SimilarityMatrix

Implements a constrained version of hierarchical agglomerative clustering, in which each observation is associated to a position, and only adjacent clusters can be merged. Typical application fields in bioinformatics include Genome-Wide Association Studies or Hi-C data analysis, where the similarity between items is a decreasing function of their genomic distance. Taking advantage of this feature, the implemented algorithm is time and memory efficient. This algorithm is described in Ambroise et al (2019) <doi:10.1186/s13015-019-0157-4>.

Version:0.6.11
Depends:R (≥ 4.0.0)
Imports:stats, graphics, grDevices,Rcpp (≥ 1.0.6),Matrix,sparseMatrixStats, methods, utils,capushe,ggplot2,dendextend,rlang
LinkingTo:Rcpp,RcppArmadillo
Suggests:knitr,testthat,rmarkdown,rioja,HiTC,snpStats,BiocGenerics
Published:2025-11-20
DOI:10.32614/CRAN.package.adjclust
Author:Christophe Ambroise [aut], Shubham Chaturvedi [aut], Alia Dehman [aut], Pierre NeuvialORCID iD [aut, cre], Guillem Rigaill [aut], Nathalie VialaneixORCID iD [aut], Gabriel Hoffman [aut]
Maintainer:Pierre Neuvial <pierre.neuvial at math.univ-toulouse.fr>
BugReports:https://github.com/pneuvial/adjclust/issues
License:GPL-3
URL:https://pneuvial.github.io/adjclust/
NeedsCompilation:yes
Language:en-US
Citation:adjclust citation info
Materials:README,NEWS
In views:Omics
CRAN checks:adjclust results

Documentation:

Reference manual:adjclust.html ,adjclust.pdf
Vignettes:Clustering of Hi-C contact maps (source,R code)
Implementation notes for the adjclust package (source,R code)
Inferring Linkage Disequilibrium blocks from genotypes (source,R code)

Downloads:

Package source: adjclust_0.6.11.tar.gz
Windows binaries: r-devel:adjclust_0.6.11.zip, r-release:adjclust_0.6.11.zip, r-oldrel:adjclust_0.6.11.zip
macOS binaries: r-release (arm64):adjclust_0.6.11.tgz, r-oldrel (arm64):adjclust_0.6.11.tgz, r-release (x86_64):adjclust_0.6.11.tgz, r-oldrel (x86_64):adjclust_0.6.11.tgz
Old sources: adjclust archive

Reverse dependencies:

Reverse imports:hicream,SISIR,treediff

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=adjclustto link to this page.


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