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PERSUADE: Parametric Survival Model Selection for Decision-Analytic Models

Provides a standardized framework to support the selection and evaluation of parametric survival models for time-to-event data. Includes tools for visualizing survival data, checking proportional hazards assumptions (Grambsch and Therneau, 1994, <doi:10.1093/biomet/81.3.515>), comparing parametric (Ishak and colleagues, 2013, <doi:10.1007/s40273-013-0064-3>), spline (Royston and Parmar, 2002, <doi:10.1002/sim.1203>) and cure models, examining hazard functions, and evaluating model extrapolation. Methods are consistent with recommendations in the NICE Decision Support Unit Technical Support Documents (14 and 21 <https://sheffield.ac.uk/nice-dsu/tsds/survival-analysis>). Results are structured to facilitate integration into decision-analytic models, and reports can be generated with 'rmarkdown'. The package builds on existing tools including 'flexsurv' (Jackson, 2016, <doi:10.18637/jss.v070.i08>)) and 'flexsurvcure' for estimating cure models.

Version:0.1.2
Depends:R (≥ 4.1.0)
Imports:data.table,flexsurv,flexsurvcure,ggplot2,muhaz,rmarkdown,rms,sft, stats,survival,survminer
Suggests:kableExtra,knitr,testthat (≥ 3.1.2), utils
Published:2025-10-09
DOI:10.32614/CRAN.package.PERSUADE
Author:Bram RamaekersORCID iD [aut, cre, ths], Xavier PouwelsORCID iD [ctb], Sabine GrimmORCID iD [ths], Manuela JooreORCID iD [ths]
Maintainer:Bram Ramaekers <bram.ramaekers at mumc.nl>
BugReports:https://github.com/Bram-R/PERSUADE/issues
License:GPL (≥ 3)
URL:https://github.com/Bram-R/PERSUADE
NeedsCompilation:no
Materials:README,NEWS
CRAN checks:PERSUADE results

Documentation:

Reference manual:PERSUADE.html ,PERSUADE.pdf
Vignettes:Introduction to PERSUADE (source,R code)

Downloads:

Package source: PERSUADE_0.1.2.tar.gz
Windows binaries: r-devel:PERSUADE_0.1.2.zip, r-release:PERSUADE_0.1.2.zip, r-oldrel:PERSUADE_0.1.2.zip
macOS binaries: r-release (arm64):PERSUADE_0.1.2.tgz, r-oldrel (arm64):PERSUADE_0.1.2.tgz, r-release (x86_64):PERSUADE_0.1.2.tgz, r-oldrel (x86_64):PERSUADE_0.1.2.tgz

Linking:

Please use the canonical formhttps://CRAN.R-project.org/package=PERSUADEto link to this page.


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