tcpl: ToxCast Data Analysis Pipeline
The ToxCast Data Analysis Pipeline ('tcpl') is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, 'invitrodb'. The package was developed for the chemical screening data curated by the US EPA's Toxicity Forecaster (ToxCast) program, but 'tcpl' can be used to support diverse chemical screening efforts.
| Version: | 3.3.1 |
| Depends: | R (≥ 4.1.0) |
| Imports: | data.table (≥ 1.15.0),DBI,RMariaDB,numDeriv,RColorBrewer, utils, stats, methods, graphics, grDevices,sqldf,dplyr,tidyr,plotly,tcplfit2,ggplot2 (≥ 3.5.2),gridExtra,stringr,rlang,ctxR (≥ 1.1.3),viridis,gt |
| Suggests: | roxygen2,knitr,prettydoc,rmarkdown,htmlTable,testthat (≥ 3.0.0),reshape2,kableExtra,colorspace,magrittr,vdiffr,httptest,rmdformats,gtable |
| Published: | 2025-10-17 |
| DOI: | 10.32614/CRAN.package.tcpl |
| Author: | Dayne L Filer [aut], Jason Brown [ctb], Madison Feshuk [cre], Carter Thunes [ctb], Sarah E Davidson-Fritz [ctb], Kelly Carstens [ctb], Elizabeth Gilson [ctb], Lindsay Knupp [ctb], Lori Kolaczkowski [ctb], Ashley Ko [ctb], Zhihui Zhao [ctb], Kurt Dunham [ctb], Todd Zurlinden [ctb], Parth Kothiya [ctb], Woodrow R Setzer [ctb], Matthew T Martin [ctb, ths], Richard S Judson [ctb, ths], Katie Paul Friedman [ctb] |
| Maintainer: | Madison Feshuk <feshuk.madison at epa.gov> |
| BugReports: | https://github.com/USEPA/CompTox-ToxCast-tcpl/issues |
| License: | MIT + fileLICENSE |
| URL: | https://github.com/USEPA/CompTox-ToxCast-tcpl,https://www.epa.gov/comptox-tools/toxicity-forecasting-toxcast |
| NeedsCompilation: | no |
| Materials: | README,NEWS |
| CRAN checks: | tcpl results |
Documentation:
| Reference manual: | tcpl.html ,tcpl.pdf |
| Vignettes: | 1. Introduction to tcpl and invitrodb (source,R code) |
Downloads:
| Package source: | tcpl_3.3.1.tar.gz |
| Windows binaries: | r-devel:tcpl_3.3.1.zip, r-release:tcpl_3.3.1.zip, r-oldrel:tcpl_3.3.1.zip |
| macOS binaries: | r-release (arm64):tcpl_3.3.1.tgz, r-oldrel (arm64):tcpl_3.3.1.tgz, r-release (x86_64):tcpl_3.3.1.tgz, r-oldrel (x86_64):tcpl_3.3.1.tgz |
| Old sources: | tcpl archive |
Reverse dependencies:
| Reverse suggests: | Rcurvep,tcplfit2,toxEval |
Linking:
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