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getspres: SPRE Statistics for Exploring Heterogeneity in Meta-Analysis

An implementation of SPRE (standardised predicted random-effects) statistics in R to explore heterogeneity in genetic association meta- analyses, as described by Magosi et al. (2019) <doi:10.1093/bioinformatics/btz590>. SPRE statistics are precision weighted residuals that indicate the direction and extent with which individual study-effects in a meta-analysis deviate from the average genetic effect. Overly influential positive outliers have the potential to inflate average genetic effects in a meta-analysis whilst negative outliers might lower or change the direction of effect. See the 'getspres' website for documentation and examples <https://magosil86.github.io/getspres/>.

Version:0.2.0
Depends:R (≥ 3.1.0)
Imports:metafor (≥ 1.9-6),dplyr (≥ 0.4.1),plotrix (≥ 3.5-12),colorspace (≥ 1.2-6),RColorBrewer (≥ 1.1-2),colorRamps (≥2.3)
Suggests:knitr (≥ 1.10.5),testthat,covr,rmarkdown
Published:2021-05-09
DOI:10.32614/CRAN.package.getspres
Author:Lerato E Magosi [aut], Jemma C Hopewell [aut], Martin Farrall [aut], Lerato E Magosi [cre]
Maintainer:Lerato E Magosi <magosil86 at gmail.com>
BugReports:https://github.com/magosil86/getspres/issues
License:MIT + fileLICENSE
URL:https://magosil86.github.io/getspres/
NeedsCompilation:no
Citation:getspres citation info
Materials:NEWS
In views:MetaAnalysis
CRAN checks:getspres results

Documentation:

Reference manual:getspres.html ,getspres.pdf
Vignettes:getspres: A simple tool to identify overly influential outlier studies in genetic association meta-analyses. (source,R code)

Downloads:

Package source: getspres_0.2.0.tar.gz
Windows binaries: r-devel:getspres_0.2.0.zip, r-release:getspres_0.2.0.zip, r-oldrel:getspres_0.2.0.zip
macOS binaries: r-release (arm64):getspres_0.2.0.tgz, r-oldrel (arm64):getspres_0.2.0.tgz, r-release (x86_64):getspres_0.2.0.tgz, r-oldrel (x86_64):getspres_0.2.0.tgz
Old sources: getspres archive

Linking:

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