DrugSim2DR: Predict Drug Functional Similarity to Drug Repurposing
A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.
| Version: | 0.1.2 |
| Depends: | R (≥ 3.6) |
| Imports: | igraph, stats,pheatmap,tidyr,reshape2,fastmatch |
| Suggests: | knitr,rmarkdown |
| Published: | 2025-10-28 |
| DOI: | 10.32614/CRAN.package.DrugSim2DR |
| Author: | Junwei Han [aut, cre, cph], Ji Li [aut], Jiashuo Wu [aut] |
| Maintainer: | Junwei Han <hanjunwei1981 at 163.com> |
| License: | GPL-2 |GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | DrugSim2DR results |
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